CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM29954
Family Name Acetylcholinesterase and Cholinesterase inhibitor hexyl (2S)-5-[2-(1-benzylpiperidin-4-yl)ethylamino]-2-[(2-methylpropan-2-yl)oxycarbonylamino]-5-oxopentanoate family
No. of Seeds 1 No. of Other Members 7
Family Centroid CFAMM00490479 Functional Category Bioactive with Natural Product
Superfamily Cholinesterase and Acetylcholinesterase Binder Superfamily 9
Class Class 506

Cousin Family NamesSeedsMembers
Angiotensin-converting enzyme inhibitor Dicarboxylate-containi... 16 374
Angiotensin-converting enzyme inhibitor Dicarboxylate-containi... 7 54
Beta-secretase 1 Inhibitor N-(1-benzylpiperidin-4-yl)-4-sulfan... 7 62
Plasmepsin-1 Inhibitor SC-5003 Family 93 173
Neuromedin-K receptor Ligand PD-157672 Family 9 37
Cathepsin K inhibitor [(3R)-4,4-dimethyl-1-phenylpentan-3-yl] ... 7 7
Chymase and Chymotrypsinogen A inhibitor tert-butyl N-[(2S)-1-... 2 7
Renin and Cathepsin D inhibitor tert-butyl N-[(2S)-1-[[(2S)-1-... 3 4
Sigma non-opioid intracellular receptor 1 ligand tert-butyl N-... 1 9
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 1 6
Gamma-secretase subunit PEN-2 inhibitor SureCN5966881 family 1 9


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00490479 CHEMBL1082081 Bioactive hexyl (2S)-5-[2-(1-benzylpiperidin-4-yl)ethylamino]-2-[(2-methylpropan-2-yl)oxycarbonylamino]-5-oxopentanoate

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27027 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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