CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM30200
Family Name Epidermal growth factor receptor and Receptor tyrosine-protein kinase erbB-2 ligand (E)-3-[3-(benzylsulfanylmethyl)-4-hydroxy-5-methoxyphenyl]-2-(3,4-dihydroxybenzoyl)prop-2-enenitrile family
No. of Seeds 1 No. of Other Members 3
Family Centroid CFAMM00491119 Functional Category Bioactive
Superfamily Aldehyde oxidase Inhibitor Isovanillin Superfamily
Class Class 663

Cousin Family NamesSeedsMembers
D-alanyl-D-alanine carboxypeptidase Inhibitor B-lactams Family 59 1364
Aldehyde oxidase Inhibitor Isovanillin Family 6 429
Multidrug resistance protein Inhibitor Curcumin I Family 19 278
Cytochrome P450 3A4 Inhibitor (-)-cubebininolide Family 4 28
Prostaglandin G/H synthase 2 Inhibitor 3,4-dibenzyloxy-2'-hydr... 7 40
CGMP-dependent protein kinase Inhibitor Tenellone A Family 1 7
Liver carboxylesterase 1 Inhibitor 2-methoxy-3,4-methylenediox... 4 26
Receptor tyrosine-protein kinase erbB-2 and Epidermal growth f... 5 0
NP 4-(3,4-dimethoxyphenyl)-4-oxo-2-(3,4,5-trimethoxyphenyl)but... 2 3


External ID

Functional Category

Molecule Name

CFAMM00491119 CHEMBL116547 Bioactive (E)-3-[3-(benzylsulfanylmethyl)-4-hydroxy-5-methoxyphenyl]-2-(3,4-dihydroxybenzoyl)prop-2-enenitrile

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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