CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM30204
Family Name Receptor tyrosine-protein kinase erbB-2 and Epidermal growth factor receptor ligand 2-Cyano-3-(4-hydroxy-3-methoxy-5-((phenylthio)methyl)phenyl)-2-propenamide family
No. of Seeds 5 No. of Other Members 0
Family Centroid CFAMM00491129 Functional Category Bioactive
Superfamily Epidermal growth factor receptor and Receptor tyrosine-protein kinase erbB-2 Binder Superfamily 5
Class Class 6103

Cousin Family NamesSeedsMembers
Transient receptor potential cation channel subfamily V member... 2 6
Epidermal growth factor receptor and Receptor tyrosine-protein... 1 3
Epidermal growth factor receptor ligand (3Z)-3-[[3-ethoxy-4-hy... 1 0


External ID

Functional Category

Molecule Name

CFAMM00491130 CHEMBL490569 Bioactive (E)-2-cyano-3-[4-hydroxy-3-phenylmethoxy-5-(phenylsulfanylmethyl)phenyl]prop-2-enamide
CFAMM00491129 CHEMBL116595 Bioactive 2-Cyano-3-(4-hydroxy-3-methoxy-5-((phenylthio)methyl)phenyl)-2-propenamide
CFAMM00491128 CHEMBL326318 Bioactive (E)-3-[3-(benzylsulfanylmethyl)-4-hydroxy-5-methoxyphenyl]-2-cyanoprop-2-enamide
CFAMM00491127 CHEMBL119987 Bioactive 2-[[5-[(E)-3-amino-2-cyano-3-oxoprop-1-enyl]-2-hydroxy-3-methoxyphenyl]methylsulfanyl]benzoic acid
CFAMM00491131 CHEMBL485070 Bioactive st 638

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

Last update by



27509 visits since 2014 .........


Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

All rights reserved.

Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links


Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543