CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM30331
Family Name Aurora kinase A inhibitor SureCN3802792 family
No. of Seeds 2 No. of Other Members 3
Family Centroid CFAMM00491471 Functional Category Bioactive with Natural Product
Superfamily Wee1-like protein kinase and Serine/threonine-protein kinase Chk1 Binder Superfamily
Class Class 2321

Cousin Family NamesSeedsMembers
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor indole... 28 2712
Cyclooxygenase Inhibitor Indomethacin Family 6 271
Integrin beta-3 Inhibitor L-756568 Family 8 59
5-hydroxytryptamine receptor 2C Ligand N-(6-phenoxypyridin-3-y... 9 69
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor lig... 7 44
Receptor-type tyrosine-protein kinase FLT3 and Vascular endoth... 4 4
D(3) dopamine receptor and 5-hydroxytryptamine receptor 1A lig... 10 50
Cellular tumor antigen p53 inhibitor CHEMBL1395699 family 1 30
Poly [ADP-ribose] polymerase 1 inhibitor SureCN5002485 family 2 11
Prelamin-A/C and Microtubule-associated protein tau inhibitor ... 1 16
Cellular tumor antigen p53 and Microtubule-associated protein ... 1 15
Vascular endothelial growth factor receptor 2 and Vascular end... 2 52
Substance-P receptor ligand 1-[4-(2-methoxyphenyl)piperazin-1-... 11 12
Histone deacetylase 3 and Histone deacetylase 9 inhibitor AGN-... 4 20
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 3 2
Melatonin receptor type 1B and Melatonin receptor type 1A liga... 3 9
Acetylcholinesterase and Cholinesterase inhibitor AGN-PC-077PI... 4 0
Vascular endothelial growth factor receptor 2 ligand SureCN235... 1 1
Platelet-derived growth factor receptor beta and Vascular endo... 1 3


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00491471 CHEMBL1214856 Bioactive SureCN3802792
CFAMM00491469 CHEMBL1214925 Bioactive SureCN3803400

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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