CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM30367
Family Name Caspase-1 inhibitor (3S)-5-[2-(1H-indol-3-yl)acetyl]oxy-4-oxo-3-(phenylmethoxycarbonylamino)pentanoic acid family
No. of Seeds 1 No. of Other Members 0
Family Centroid CFAMM00491600 Functional Category Bioactive
Superfamily Renin and Caspase-1 Binder Superfamily
Class Class 247

Cousin Family NamesSeedsMembers
5-hydroxytryptamine receptor 3A Ligand Dolasetron Family 12 171
Indoleamine 2,3-dioxygenase 1 Inhibitor L-tryptophan Family 8 328
Substance-P receptor Ligand GSK424887 Family 8 184
Gastrin/cholecystokinin type B receptor Ligand PD136450 Family 53 117
Lethal factor Inhibitor GM6001 Family 50 435
Substance-K receptor and Substance-P receptor Ligand L-732138 ... 8 147
Cathepsin B and Cathepsin K Inhibitor Z-arg-leu-val-agly-ile-v... 3 19
Angiotensin-converting enzyme and Endothelin-converting enzyme... 2 10
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 24 64
Endothelin B receptor Ligand IRL-2500 Family 34 87
C-C chemokine receptor type 5 ligand AC1LAJEM family 4 14
Pol polyprotein inhibitor pyridin-2-ylmethyl N-[(2R)-1-[[(2S,3... 15 8
Neutrophil collagenase and Stromelysin-3 inhibitor AC1MORIH fa... 7 9
Calpain-1 catalytic subunit and Cathepsin B inhibitor AGN-PC-0... 5 2
Cholecystokinin receptor type A and Gastrin/cholecystokinin ty... 4 53
Growth hormone-releasing hormone receptor ligand ethyl (1S)-1'... 3 2
Neutrophil collagenase and Stromelysin-3 inhibitor [3-[[1-amin... 3 2
Cyclin-dependent kinase 2 and Vascular endothelial growth fact... 1 1
Calcium/calmodulin-dependent protein kinase type II subunit de... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00491600 CHEMBL1222835 Bioactive (3S)-5-[2-(1H-indol-3-yl)acetyl]oxy-4-oxo-3-(phenylmethoxycarbonylamino)pentanoic acid

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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