CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM3044
Family Name Prelamin-A/C and Survival motor neuron protein inhibitor CHEMBL1320403 family
No. of Seeds 1 No. of Other Members 3
Family Centroid CFAMM00342731 Functional Category Bioactive
Superfamily Huntingtin and Prelamin-A/C Binder Superfamily 5
Class Class 586

Cousin Family NamesSeedsMembers
Vasopressin V1a receptor Ligand Felypressin Family 12 820
Sodium channel protein type 5 subunit alpha Ligand Mephenytoin... 5 51
Alpha-1B adrenergic receptor Ligand Lisdexamfetamine Family 14 443
Glutathione S-transferase Inhibitor Praziquantel Family 5 167
Tumor necrosis factor Inhibitor Thalidomide Family 3 50
Acetylcholinesterase Inhibitor Ambenonium Family 4 71
DNA Binder Procarbazine Family 8 358
5-hydroxytryptamine receptor 2A and D(2) dopamine receptor Lig... 2 18
5-hydroxytryptamine receptor 2A Ligand N-(1-(1-phenylethyl)pip... 22 207
Dipeptidyl peptidase 4 Inhibitor Denagliptin Family 24 151
Hemagglutinin Inhibitor Cl 385319 Family 18 101
Prothrombin Inhibitor Efegatran Family 9 47
Neutrophil elastase Inhibitor FK-706 Family 8 85
Prothrombin Inhibitor D-leucyl-n-(3-chlorobenzyl)-l-prolinamid... 18 168
Prothrombin Inhibitor D-leucyl-n-(4-carbamimidoylbenzyl)-l-pro... 13 44
Beta-secretase 1 Inhibitor N-(1-benzylpiperidin-4-yl)-4-sulfan... 7 62
Histone deacetylase 1 Inhibitor 8-(3-benzoyl-ureido)-octanoic ... 7 13
Aromatase Inhibitor 3-(4-amino-phenyl)-1-methyl-pyrrolidine-2,... 4 8
Neuromedin-K receptor Ligand PD-157672 Family 9 37
Histone deacetylase 1 and Histone deacetylase 2 Inhibitor N-(6... 1 12
Cathepsin K and Cathepsin L1 Inhibitor N-benzoyl-phenylalanyl-... 13 77
Dipeptidyl peptidase 4 Inhibitor N4-(4-chlorobenzyl)-2,4-diami... 10 22
D(2) dopamine receptor and D(3) dopamine receptor Ligand ST-19... 5 27
Sodium-dependent dopamine transporter and Sodium-dependent nor... 28 71
Cannabinoid receptor 1 Ligand N-(3,3-diphenyl)propyl-2-phenyla... 4 18
Muscarinic acetylcholine receptor M4 and Muscarinic acetylchol... 20 55
Baculoviral IAP repeat-containing protein 3 and E3 ubiquitin-p... 44 28
Aminopeptidase N Inhibitor N1,2-dibenzyl-n3-hydroxymalonamide ... 5 23
Arachidonate 5-lipoxygenase Inhibitor N-hydroxy-n-methyl-benza... 3 9
Sodium channel protein type 1 subunit alpha and Sodium channel... 4 31
Muscarinic acetylcholine receptor M1 and Muscarinic acetylchol... 2 80
Melatonin receptor type 1A Ligand N-(2,3-dihydro-1h-phenalen-2... 8 13
Aminopeptidase N Inhibitor 2-amino-n1-benzyl-n3-hydroxymalonam... 3 4
Aminopeptidase N Inhibitor 2-benzyl-n1-hydroxy-n3-(4-phenylbut... 5 3
Prolyl endopeptidase Inhibitor SUAM-1221 Family 42 47
Aminopeptidase N Inhibitor 2-cinnamamido-n4-hexyl-n1-hydroxysu... 24 8
Cholecystokinin receptor type A Ligand CR-1795 Family 19 41
Dipeptidyl peptidase 4 inhibitor (2S)-1-[(2S,4S,5S)-4-(1,3-dih... 3 14
Dipeptidyl peptidase 4 and Dipeptidyl peptidase 8 inhibitor (2... 5 3
Cathepsin K inhibitor [(3R)-4,4-dimethyl-1-phenylpentan-3-yl] ... 7 7
Cathepsin K and Cathepsin S inhibitor 1-benzyl-3-[(2S)-1-[[cya... 1 0
Metabotropic glutamate receptor 5 ligand SureCN504295 family 1 7
Dipeptidyl peptidase 8 inhibitor (2S)-2-amino-4-[4-[bis(4-fluo... 2 9
Dipeptidyl peptidase 4 inhibitor SureCN2709139 family 5 7
Dipeptidyl peptidase 2 and Dipeptidyl peptidase 4 inhibitor (2... 3 10
Kinesin-like protein KIF11 and Potassium voltage-gated channel... 4 1
Peptide deformylase inhibitor (2S)-N-benzoyl-1-[(2R)-2-(cyclop... 2 2
Substance-P receptor ligand (3R,4R)-1-(1-acetylpiperidine-4-ca... 9 1
Dipeptidyl peptidase 4 inhibitor 4-cyano-N-[4-[(2S)-2-cyanopyr... 1 1
Histamine H3 receptor ligand N-ethyl-3-fluoro-3-[3-fluoro-4-(p... 3 0
Cathepsin K and Cathepsin S inhibitor (1R,2R)-N-(cyanomethyl)-... 1 0
P2X purinoceptor 7 inhibitor SureCN8516206 family 5 1
P2X purinoceptor 7 inhibitor (4S)-3-methyl-N-[[2-methyl-3-(tri... 3 0
Baculoviral IAP repeat-containing protein 3 and E3 ubiquitin-p... 3 1
Dipeptidyl peptidase 4 and Dipeptidyl peptidase 8 inhibitor (2... 3 0
Tryptase alpha/beta-1 and Trypsin-1 inhibitor AGN-PC-074JFM fa... 3 1
Dipeptidyl peptidase 2 and Dipeptidyl peptidase 4 inhibitor Su... 1 1
Prolyl endopeptidase and Seprase inhibitor [(2R)-1-[2-[benzoyl... 2 0
Sodium-dependent noradrenaline transporter and Muscarinic acet... 1 2
Dipeptidyl peptidase 4 and Dipeptidyl peptidase 9 inhibitor N-... 9 0
C-C chemokine receptor type 5 ligand N-[(1S)-3-[(3aS,6aR)-5-(2... 1 0
P2X purinoceptor 7 inhibitor SureCN2574353 family 1 1
NS3 inhibitor 6-[[(2S)-1-[[(2S)-1-[(2S)-2-[[1-(cyclopropylamin... 2 0
Trypsin-1 and Prothrombin inhibitor N-[(1R)-4-(diaminomethylid... 1 0
Dipeptidyl peptidase 4 inhibitor (2S,4S)-4-fluoro-1-[2-[[(E)-2... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00342733 CHEMBL189463 Bioactive N-benzyl-5-(pyrrolidine-1-carbonyl)cyclopentene-1-carboxamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27511 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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