CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM30470
Family Name Sodium-dependent dopamine transporter inhibitor methyl (2R)-2-(3,4-dimethoxyphenyl)-2-[(2R)-piperidin-2-yl]acetate family
No. of Seeds 4 No. of Other Members 3
Family Centroid CFAMM00491960 Functional Category Bioactive with Natural Product
Superfamily Prelamin-A/C and Beta-lactamase Binder Superfamily 22
Class Class 333

Cousin Family NamesSeedsMembers
Angiotensin-converting enzyme Inhibitor Moexipril Family 5 469
Beta adrenergic receptor Ligand Dipivefrin Family 3 55
Synaptic vesicular amine transporter Inhibitor Tetrabenazine F... 13 425
Muscarinic acetylcholine receptor Ligand Mebeverine Family 2 27
Melatonin receptor type 1A Ligand Agomelatine Family 12 164
Substance-P receptor Ligand DA-5018 Family 14 73
D(3) dopamine receptor Ligand U-99194A Family 7 33
Ivabradine family 1 11
Cannabinoid receptor 1 Ligand N-(3,5-dimethoxyphenethyl)oleami... 5 49
Cannabinoid receptor 1 Ligand N-(4-methoxyphenethyl)oleamide F... 10 36
Fatty-acid amide hydrolase 1 Inhibitor 3'-carbamoylbiphenyl-3-... 8 50
Fatty-acid amide hydrolase 1 Inhibitor 4-(cyclohexylmethylcarb... 2 4
Sodium-dependent dopamine transporter Inhibitor (+/-)-threo-n-... 24 73
Glycine receptor subunit beta Ligand ORG-25543 Family 10 153
Transient receptor potential cation channel subfamily V member... 3 18
Kappa-type opioid receptor and Delta-type opioid receptor liga... 1 3
Follicle-stimulating hormone receptor ligand SureCN6140614 family 2 8
Integrin beta-3 and Integrin alpha-IIb inhibitor (3R)-3-(1,3-b... 4 2
Cathepsin K inhibitor (2S)-2-[[2-(3,4-dimethoxyphenyl)acetyl]a... 1 1
Beta-2 adrenergic receptor and Beta-1 adrenergic receptor liga... 1 3
Carbonic anhydrase and Carbonic anhydrase 2 inhibitor 2-(3-chl... 2 0
Chymase and Chymotrypsinogen A inhibitor N-[(2S)-4-chloro-3-ox... 1 0
NP (z)-n-((4-(3,4-dimethoxyphenyl)tetrahydro-2h-pyran-4-yl)met... 3 2
3-benzazepin-2-one NP 7,8-dimethoxy-1h-benzo[d]azepin-2(3h)-on... 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00491960 CHEMBL1254516 Bioactive methyl (2R)-2-(3,4-dimethoxyphenyl)-2-[(2R)-piperidin-2-yl]acetate
CFAMM00491965 CHEMBL1253212 Bioactive methyl (2R)-2-(3-methoxyphenyl)-2-[(2R)-2-methylpiperidin-2-yl]acetate
CFAMM00491963 CHEMBL553985 Bioactive methyl (2S)-2-(3-methoxyphenyl)-2-[(2S)-piperidin-2-yl]acetate;hydrochloride
CFAMM00491962 CHEMBL543502 Bioactive methyl (2S)-2-(3,4-dimethoxyphenyl)-2-[(2S)-piperidin-2-yl]acetate;hydrochloride

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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