CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM305
Family Name Peroxisome proliferator-activated receptor delta ligand SureCN14384341 family
No. of Seeds 8 No. of Other Members 19
Family Centroid CFAMM00310076 Functional Category Bioactive
Superfamily Peroxisome proliferator-activated receptor delta and Peroxisome proliferator-activated receptor alpha Binder Superfamily
Class Class 994

Cousin Family NamesSeedsMembers
Cyclooxygenase Inhibitor Oxaprozin Family 33 450
Phospholipase A2, membrane associated Inhibitor Varespladib Fa... 37 190
Peroxisome proliferator-activated receptor alpha Ligand Alegli... 29 7
Substance-P receptor Ligand R 673 Family 2 127
Peroxisome proliferator-activated receptor gamma and Peroxisom... 15 94
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 7 37
Fatty-acid amide hydrolase 1 Inhibitor 1-(oxazolo[4,5-b]pyridi... 19 34
Fatty-acid amide hydrolase 1 Inhibitor 1-(5-(pyridin-2-yl)oxaz... 10 142
Oestrogen receptor and Estrogen receptor beta Ligand 2-(6-hydr... 9 22
Prostacyclin receptor and Prostaglandin E2 receptor EP3 subtyp... 4 17
Neutrophil elastase Inhibitor Cbz-val-pro-val-(2-benzoxazole) ... 32 64
Estradiol 17-beta-dehydrogenase 1 Inhibitor 3-[5-(4-hydroxyphe... 4 36
Adenosine receptor A1 and Adenosine receptor A2a Ligand N-(2-(... 21 108
Peroxisome proliferator-activated receptor alpha Ligand BMS-68... 10 16
Fatty-acid amide hydrolase 1 Inhibitor 1-(5-(furan-2-yl)oxazol... 2 1
Peroxisome proliferator-activated receptor delta ligand AGN-PC... 7 27
Peroxisome proliferator-activated receptor delta and Peroxisom... 2 7
Muscarinic acetylcholine receptor M3 ligand [(3R)-1-[3-(1,3-be... 3 2
Histamine H3 receptor and Potassium voltage-gated channel subf... 2 21
Phospholipase A2 inhibitor SureCN7046992 family 2 3
Collagenase 3 inhibitor N-[[3-[5-[[(1R)-1-cyclohexyl-2-(methyl... 6 9
Histone deacetylase 1 and Histone deacetylase 2 inhibitor AGN-... 4 15
Leukotriene B4 receptor 1 and Leukotriene B4 receptor 2 ligand... 4 14
Prelamin-A/C inhibitor CHEMBL1374443 family 1 6
Ferritin light chain and Ras-related protein Rab-9A inhibitor ... 1 11
Retinoic acid receptor beta and Retinoic acid receptor alpha l... 2 2
Thromboxane-A synthase and Thromboxane A2 receptor ligand Sure... 5 37
Inosine-5'-monophosphate dehydrogenase inhibitor SureCN1318237... 2 12
Histamine H3 receptor ligand SureCN2784306 family 5 3
Prostaglandin D2 receptor ligand 2-methoxy-N-[2-(4-methoxyphen... 2 2
Fatty-acid amide hydrolase 1 inhibitor 3-[(3R)-1-[4-(1-benzofu... 4 4
Fatty-acid amide hydrolase 1 inhibitor methyl 6-[2-[3-(4-pheny... 8 5
Fatty-acid amide hydrolase 1 inhibitor [(2S)-6-phenoxy-1,2,3,4... 3 6
Peroxisome proliferator-activated receptor gamma ligand AGN-PC... 5 12
Fatty-acid amide hydrolase 1 and Liver carboxylesterase 1 inhi... 2 2
Integrin beta-1 and Integrin alpha-4 inhibitor 4-[[(2S,4S)-4-f... 4 7
Peroxisome proliferator-activated receptor gamma and Peroxisom... 4 1
Sphingosine 1-phosphate receptor 1 ligand 6-[2-[6-propan-2-ylo... 1 1
Sphingosine 1-phosphate receptor 1 ligand 6-[2-[4-phenyl-3-(tr... 2 3
Sphingosine 1-phosphate receptor 1 and Sphingosine 1-phosphate... 14 24
Peroxisome proliferator-activated receptor gamma and Peroxisom... 1 3
Potassium voltage-gated channel subfamily H member 2 and 5-hyd... 2 2
Peroxisome proliferator-activated receptor alpha and Peroxisom... 5 2
Peroxisome proliferator-activated receptor gamma and Peroxisom... 10 5
Peroxisome proliferator-activated receptor gamma and Peroxisom... 3 0
Fatty-acid amide hydrolase 1 inhibitor alpha-ketooxazole, 4jj ... 1 1
Fatty-acid amide hydrolase 1 inhibitor alpha-ketooxazole, 5a f... 2 1
Peroxisome proliferator-activated receptor gamma and Peroxisom... 5 0
Inosine-5'-monophosphate dehydrogenase inhibitor (2S)-2-(2,3-d... 4 1
Inosine-5'-monophosphate dehydrogenase inhibitor (2S)-2-naphth... 1 0
Integrin beta-1 and Integrin alpha-4 inhibitor (2S)-2-[[2-(die... 12 2
Beta-2 adrenergic receptor and Beta-3 adrenergic receptor liga... 1 5
Peroxisome proliferator-activated receptor alpha ligand 5-[4-[... 1 0
D(2) dopamine receptor and 5-hydroxytryptamine receptor 1A lig... 11 3
Mitogen-activated protein kinase 14 inhibitor 4-[4-(4-fluoroph... 1 5
Peroxisome proliferator-activated receptor gamma and Peroxisom... 7 2
Rho-associated protein kinase 2 inhibitor SureCN3232097 family 1 1
Fatty-acid amide hydrolase 1 inhibitor AGN-PC-04UH7Y family 4 1
Leukotriene A-4 hydrolase inhibitor SureCN3030546 family 9 1
Peroxisome proliferator-activated receptor gamma and Peroxisom... 4 3
Metabotropic glutamate receptor 5 ligand 3-fluoro-5-(5-pyridin... 1 0
Diacylglycerol O-acyltransferase 1 inhibitor 3-[[1-[5-[[2-(3-m... 1 1
Fatty-acid amide hydrolase 1 inhibitor 7-phenyl-1-[5-[6-(2H-te... 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00310074 CHEMBL1075895 Bioactive SureCN14384347
CFAMM00310072 CHEMBL1075894 Bioactive SureCN14384348
CFAMM00310076 CHEMBL1080173 Bioactive SureCN14384341
CFAMM00310054 CHEMBL1080109 Bioactive SureCN5586021

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27029 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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