CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM30506
Family Name Farnesyl pyrophosphate synthase inhibitor AGN-PC-080IBX family
No. of Seeds 2 No. of Other Members 0
Family Centroid CFAMM00492058 Functional Category Bioactive
Superfamily Farnesyl pyrophosphate synthase and Neprilysin Binder Superfamily
Class Class 1116

Cousin Family NamesSeedsMembers
Potassium voltage-gated channel subfamily KQT member 1 Ligand ... 13 242
TGF-beta receptor type-1 Ligand 4-(3-pyridin-2-yl-1h-pyrazol-4... 3 63
TGF-beta receptor type-1 Ligand Naphthyridine Inhibitor Family 3 6
Metabotropic glutamate receptor 5 Ligand 3-(3-pyridin-2-yl-pyr... 4 24
D(2) dopamine receptor and D(3) dopamine receptor Ligand 1-(4-... 10 48
Indoleamine 2,3-dioxygenase 1 Inhibitor 4-(1h-1,2,3-triazol-5-... 3 12
Histamine H3 receptor and Potassium voltage-gated channel subf... 4 33
Serine/threonine-protein kinase B-raf inhibitor AGN-PC-00AP1L ... 14 7
Serine/threonine-protein kinase B-raf and Mitogen-activated pr... 16 5


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00492057 CHEMBL1258422 Bioactive AGN-PC-080IBY
CFAMM00492058 CHEMBL1258421 Bioactive AGN-PC-080IBX

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26820 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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