CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM30531
Family Name Induced myeloid leukemia cell differentiation protein Mcl-1 and Bcl-2-like protein 1 inhibitor SureCN1893025 family
No. of Seeds 6 No. of Other Members 13
Family Centroid CFAMM00492134 Functional Category Bioactive with Human Metabolite & Natural Product
Superfamily DNA topoisomerase 2-beta and Oxysterols receptor LXR-alpha Binder Superfamily
Class Class 125

Cousin Family NamesSeedsMembers
Retinoid X receptor Ligand Bexarotene Family 7 492
Estrogen receptor beta Ligand Conjugated Estrogens Family 12 210
Danthron family 11 141
Apoptosis regulator Bcl-2 Inhibitor Gossypol Family 1 9
Glucose-6-phosphate translocase Inhibitor Mumbaistatin Family 3 11
Epidermal growth factor receptor Ligand AG-538 Family 5 11
Estrogen receptor beta Ligand 3,6-dihydroxy-2-(4-hydroxy-pheny... 2 23
L-selectin and P-selectin Inhibitor 2,3,4-trihydroxybenzoic Ac... 2 10
Estradiol 17-beta-dehydrogenase 1 Inhibitor 3-(6-hydroxy-2-nap... 7 9
DNA topoisomerase 2-beta Inhibitor Demethylzeylasterone Family 1 2
Cannabinoid receptor 2 Ligand 2-(2-methoxybenzyl)-3h-benzo[f]c... 6 32
Arachidonate 12-lipoxygenase, 12S-type and Arachidonate 15-lip... 3 7
Indoleamine 2,3-dioxygenase 1 Inhibitor Garveatin E Family 2 0
Tyrosine-protein phosphatase non-receptor type 1 Ligand Kuwano... 3 3
Aldehyde dehydrogenase, cytosolic 1 and Aldehyde dehydrogenase... 2 0


External ID

Functional Category

Molecule Name

CFAMM00492118 CHEMBL1272170 Bioactive 6,6',7,7'-Tetrahydroxy-5,5'-diisopropyl-3,3'-dimethyl-[2,2'-binaphthalene]-1,1',4,4'-tetraone
CFAMM00492141 CHEMBL1269107 Bioactive AGN-PC-088HBC
CFAMM00492116 CHEMBL1269110 Bioactive SureCN1887255
CFAMM00492135 CHEMBL1269077 Bioactive SureCN1889138
CFAMM00492124 CHEMBL1272224 Bioactive SureCN1890942
CFAMM00492134 CHEMBL1269075 Bioactive SureCN1893025

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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