CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM30573
Family Name Dipeptidyl peptidase 4 inhibitor 7-[(3R)-3-amino-4-(2,4,5-trifluorophenyl)butanoyl]-2-[(4-methoxyphenyl)methyl]-5,6,8,8a-tetrahydro-1H-imidazo[1,5-a]pyrazin-3-one;(E)-but-2-enedioic acid family
No. of Seeds 2 No. of Other Members 0
Family Centroid CFAMM00492221 Functional Category Bioactive
Superfamily Dipeptidyl peptidase 4 and Neuropeptide S receptor Binder Superfamily
Class Class 906

Cousin Family NamesSeedsMembers
Angiotensin-converting enzyme Inhibitor Moexipril Family 5 469
Zucapsacin family 7 177
Serine/threonine-protein kinase PLK1 Inhibitor On 019190.na Fa... 16 138
Growth hormone secretagogue receptor type 1 Ligand TZP-101 Family 28 263
A disintegrin and metalloproteinase with thrombospondin motifs... 7 119
C-C chemokine receptor type 5 Ligand E-913 Family 6 44
Voltage-dependent L-type calcium channel Ligand PD173212 Family 24 104
Disintegrin and metalloproteinase domain-containing protein 17... 25 36
Potassium voltage-gated channel subfamily A member 3 Ligand 2-... 9 92
Cannabinoid receptor 1 Ligand N-(4-methoxyphenethyl)oleamide F... 10 36
Voltage-dependent T-type calcium channel subunit alpha-1H Liga... 5 26
Oxytocin receptor Ligand [mpa1, D-tyr(et)2, D-tic7]ot Family 43 26
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 95 46
Neutrophil elastase inhibitor (2S)-N-[(3S)-6-benzamido-5,5-dif... 6 10
3-hydroxyacyl-CoA dehydrogenase type-2 and Retinal dehydrogena... 1 15
Stromelysin-1 and Matrix metalloproteinase-9 inhibitor AGN-PC-... 26 12
Growth hormone secretagogue receptor type 1 ligand tert-butyl ... 5 4
Cathepsin K and Cathepsin S inhibitor (1R,2R)-N-[cyano-(2-meth... 1 0
Baculoviral IAP repeat-containing protein 3 and E3 ubiquitin-p... 7 1
Neuropeptide Y receptor type 1 and Sodium-dependent serotonin ... 2 7


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00492221 CHEMBL1275851 Bioactive 7-[(3R)-3-amino-4-(2,4,5-trifluorophenyl)butanoyl]-2-[(4-methoxyphenyl)methyl]-5,6,8,8a-tetrahydro-1H-imidazo[1,5-a]pyrazin-3-one;(E)-but-2-enedioic acid
CFAMM00492220 CHEMBL1275854 Bioactive 7-[(3R)-3-amino-4-(2,4,5-trifluorophenyl)butanoyl]-2-[(3,5-dimethoxyphenyl)methyl]-5,6,8,8a-tetrahydro-1H-imidazo[1,5-a]pyrazin-3-one;(E)-but-2-enedioic acid

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27036 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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