CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM3069
Family Name Pol polyprotein inhibitor 3-[[(4R,5S,6S,7R)-4,7-dibenzyl-3-(3,5-dimethoxyphenyl)-5,6-dihydroxy-2-oxo-1,3-diazepan-1-yl]methyl]-N-pyridin-2-ylbenzamide family
No. of Seeds 12 No. of Other Members 1
Family Centroid CFAMM00343095 Functional Category Bioactive
Superfamily Pol polyprotein and Histamine H1 receptor Binder Superfamily
Class Class 1612

Cousin Family NamesSeedsMembers
Adenosine receptor A1 and Adenosine receptor A3 Ligand 4-metho... 1 16
Integrin beta-1 and Integrin alpha-5 inhibitor (2S)-2-[(4-fluo... 7 1
Cathepsin E and Cathepsin D inhibitor SureCN2530955 family 3 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00343098 CHEMBL335424 Bioactive AC1LAFWE
CFAMM00343091 CHEMBL339147 Bioactive AC1LAFVZ
CFAMM00343097 CHEMBL88016 Bioactive 3-[[(4R,5S,6S,7R)-4,7-dibenzyl-3-(3,5-dimethoxyphenyl)-5,6-dihydroxy-2-oxo-1,3-diazepan-1-yl]methyl]-N-(6-methylpyridin-2-yl)benzamide
CFAMM00343090 CHEMBL336885 Bioactive AC1LAFWB
CFAMM00343096 CHEMBL86368 Bioactive 3-[[(4R,5S,6S,7R)-4,7-dibenzyl-3-(3,5-dimethoxyphenyl)-5,6-dihydroxy-2-oxo-1,3-diazepan-1-yl]methyl]-N-(5-methylpyridin-2-yl)benzamide
CFAMM00343095 CHEMBL316408 Bioactive 3-[[(4R,5S,6S,7R)-4,7-dibenzyl-3-(3,5-dimethoxyphenyl)-5,6-dihydroxy-2-oxo-1,3-diazepan-1-yl]methyl]-N-pyridin-2-ylbenzamide
CFAMM00343088 CHEMBL132175 Bioactive AC1LAFVW
CFAMM00343094 CHEMBL335935 Bioactive AC1LAFWH
CFAMM00343087 CHEMBL438727 Bioactive 3-[[(4R,5S,6S,7R)-4,7-dibenzyl-5,6-dihydroxy-3-(3-methoxyphenyl)-2-oxo-1,3-diazepan-1-yl]methyl]-N-(5-methylpyridin-2-yl)benzamide
CFAMM00343093 CHEMBL316375 Bioactive 3-[[(4R,5S,6S,7R)-4,7-dibenzyl-5,6-dihydroxy-3-(3-methoxyphenyl)-2-oxo-1,3-diazepan-1-yl]methyl]-N-(6-methylpyridin-2-yl)benzamide
CFAMM00343099 CHEMBL313003 Bioactive 3-[[(4R,5S,6S,7R)-4,7-dibenzyl-5,6-dihydroxy-3-(3-methoxyphenyl)-2-oxo-1,3-diazepan-1-yl]methyl]-N-pyridin-2-ylbenzamide
CFAMM00343092 CHEMBL436577 Bioactive AC1LAFW5

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

71834 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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