CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM30835
Family Name Nuclear receptor ROR-gamma and Prelamin-A/C ligand CHEMBL1446115 family
No. of Seeds 1 No. of Other Members 18
Family Centroid CFAMM00492778 Functional Category Bioactive with Natural Product
Superfamily Prelamin-A/C and Nociceptin receptor Binder Superfamily
Class Class 3210

Cousin Family NamesSeedsMembers
HIV protease Inhibitor Saquinavir Family 64 428
Potassium voltage-gated channel subfamily KQT member 1 Ligand ... 13 242
D(1B) dopamine receptor Ligand LE-300 Family 65 452
CP-18770 family 6 27
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 6 17
Fibroblast growth factor receptor 2 Ligand Interferon Alfa (if... 14 162
Fatty acid-binding protein, adipocyte and Fatty acid-binding p... 3 11
Cholecystokinin receptor type A Ligand VL-0395 Family 12 117
Inosine-5'-monophosphate dehydrogenase 2 Inhibitor 1-methyl-1h... 6 24
Cholinesterase Inhibitor 9-[9-(beta-carboline-9-yl)nonyl]-beta... 7 7
14-alpha sterol demethylase Inhibitor CP-320626 Family 13 76
Kappa-type opioid receptor and Mu-type opioid receptor Ligand ... 19 108
Ribosyldihydronicotinamide dehydrogenase [quinone] Inhibitor N... 6 10
Histamine H3 receptor and Potassium voltage-gated channel subf... 1 3
Pol polyprotein inhibitor N-[(2S)-1-[[(2S,3R,4S,5S)-3,4-dihydr... 2 0
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 11 20
D(2) dopamine receptor and 5-hydroxytryptamine receptor 2C lig... 2 3
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 13 1
Melanin-concentrating hormone receptor 1 ligand AGN-PC-09M6QF ... 3 0
D(2) dopamine receptor and 5-hydroxytryptamine receptor 1A lig... 5 8
Cannabinoid receptor 1 ligand 5-cyano-N-(3-hydroxy-2,2-dimethy... 4 2
CGMP-dependent protein kinase inhibitor AGN-PC-075XII family 25 7
Melanin-concentrating hormone receptor 2 ligand N-[(1R)-1'-(9H... 4 1
Cannabinoid receptor 1 ligand N-[2-(cyclopropylamino)-2-oxoeth... 5 5
Egl nine homolog 1 inhibitor 1'-[(3-methylpyridin-2-yl)methyl]... 6 4
5-hydroxytryptamine receptor 1D ligand AGN-PC-01NTBS family 1 1
Thromboxane-A synthase inhibitor AGN-PC-07BYVF family 1 0
Sodium-dependent noradrenaline transporter and Sodium-dependen... 5 7
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 1 1
Nonstructural protein 1 and Lysine-specific demethylase 4E inh... 1 0
Cytochrome P450 2C19 inhibitor CHEMBL1449918 family 1 0
Voltage-dependent N-type calcium channel subunit alpha-1B liga... 2 0
NP (e)-9-(2-methoxy-2-(prop-1-en-1-yloxy)ethyl)-9h-carbazole F... 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00492773 CHEMBL2059101 Bioactive 1,3-di(carbazol-9-yl)propan-2-ol

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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