CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM3093
Family Name Poly [ADP-ribose] polymerase 1 inhibitor ethyl 4-(4-carbamoyl-1H-benzimidazol-2-yl)benzoate family
No. of Seeds 2 No. of Other Members 15
Family Centroid CFAMM00343283 Functional Category Bioactive with Natural Product
Superfamily Poly [ADP-ribose] polymerase 1 Inhibitor 2-(3'-methoxyphenyl) Benzimidazole-4-carboxamide Superfamily
Class Class 1456

Cousin Family NamesSeedsMembers
Vasopressin V1a receptor and Vasopressin V2 receptor Ligand be... 4 301
Type-1 angiotensin II receptor Ligand Telmisartan Family 4 181
Tubulin beta chain Inhibitor Mebendazole Family 12 84
CC-486 family 7 103
Poly [ADP-ribose] polymerase 1 Inhibitor 2-(3'-methoxyphenyl) ... 9 93
Vascular endothelial growth factor receptor 2 Ligand 6-(1h-ben... 2 5
DNA (cytosine-5)-methyltransferase 3B Inhibitor NSC-57893 Family 3 8
Poly [ADP-ribose] polymerase 1 inhibitor 2-(3-chlorophenyl)-1H... 4 38
Type-1A angiotensin II receptor and Type-1B angiotensin II rec... 2 9
Poly [ADP-ribose] polymerase 1 inhibitor SureCN6202744 family 4 2
Adenosine receptor A2b and Adenosine receptor A1 ligand MRS 17... 10 0
Adenosine receptor A2a and Adenosine receptor A2b ligand SureC... 2 2
Serine/threonine-protein kinase Chk2 inhibitor SureCN3919556 f... 4 8
5-hydroxytryptamine receptor 4 ligand AGN-PC-00PM3Y family 4 3
Gastrin/cholecystokinin type B receptor ligand 3-[[5-[2-(1-ada... 9 15
Casein kinase II subunit alpha and Serine/threonine-protein ki... 1 5
Vascular endothelial growth factor receptor 2 ligand (3Z)-6-fl... 4 3
Platelet-derived growth factor receptor beta and Vascular endo... 5 12
Smoothened homolog inhibitor N-[3-(1H-benzimidazol-2-yl)phenyl... 2 1
B1 bradykinin receptor ligand methyl 2-[4-[(1R)-1-[[3-[(2-cyan... 8 7
Smoothened homolog inhibitor N-[4-methyl-3-(5-phenyl-1H-imidaz... 1 0
Melanocortin receptor 4 ligand AGN-PC-076AMT family 2 9
5-hydroxytryptamine receptor 4 and 5-hydroxytryptamine recepto... 10 1
cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-speci... 1 0
Histamine H3 receptor ligand AGN-PC-075YVW family 1 2
Neuropeptide Y receptor type 5 ligand AGN-PC-077LY9 family 5 5
Neuropeptide Y receptor type 5 ligand 1'-(5-CHLORO-1H-BENZIMID... 4 1
Neuropeptide Y receptor type 5 ligand AGN-PC-02WBQH family 7 1
Neuropeptide Y receptor type 5 ligand AGN-PC-077LX1 family 8 1
Neuropeptide Y receptor type 5 ligand AGN-PC-077LYW family 3 1
Serine/threonine-protein kinase Sgk1 inhibitor SureCN3774571 f... 2 18
Poly [ADP-ribose] polymerase 1 inhibitor AGN-PC-077D0D family 3 0
Poly [ADP-ribose] polymerase 1 inhibitor 2-[4-(1,2-oxazol-5-yl... 2 1
Poly [ADP-ribose] polymerase 1 inhibitor 2-[4-(5-sulfanylidene... 1 1
Poly [ADP-ribose] polymerase 1 and Poly [ADP-ribose] polymeras... 4 0
Poly [ADP-ribose] polymerase 1 inhibitor AGN-PC-077DC5 family 2 2
Histamine H3 receptor ligand SureCN7961030 family 1 2
Prelamin-A/C and Microtubule-associated protein tau inhibitor ... 1 5


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00343276 CHEMBL576910 Bioactive 2-[4-(2-oxo-3H-1,3,4-oxadiazol-5-yl)phenyl]-1H-benzimidazole-4-carboxamide
CFAMM00343283 CHEMBL133855 Bioactive ethyl 4-(4-carbamoyl-1H-benzimidazol-2-yl)benzoate

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27525 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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