CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM3096
Family Name Survival motor neuron protein inhibitor CHEMBL1323700 family
No. of Seeds 1 No. of Other Members 4
Family Centroid CFAMM00343298 Functional Category Bioactive
Superfamily Glutathione S-transferase Inhibitor Praziquantel Superfamily
Class Class 107

Cousin Family NamesSeedsMembers
Sodium channel Ligand hydantoin derivative Phenytoin Family 2 25
Vasopressin V1a receptor Ligand Felypressin Family 12 820
Sodium channel protein type 5 subunit alpha Ligand Indecainide... 2 41
Sodium channel protein type 5 subunit alpha Ligand Mephenytoin... 5 51
Alpha-1B adrenergic receptor Ligand Lisdexamfetamine Family 14 443
Glutathione S-transferase Inhibitor Praziquantel Family 5 167
Substance-P receptor Ligand Vestipitant Family 14 137
Neuropeptide Y receptor type 1 Ligand BIBO3304 Family 4 69
5-hydroxytryptamine receptor 2A Ligand N-(1-(1-phenylethyl)pip... 22 207
Melanocortin receptor 4 Ligand Ro-27-3225 Family 6 52
Dipeptidyl peptidase 4 Inhibitor Denagliptin Family 24 151
Prothrombin Inhibitor Efegatran Family 9 47
Neutrophil elastase Inhibitor FK-706 Family 8 85
Prothrombin Inhibitor LB30812 Family 12 36
Prothrombin Inhibitor Ppack Family 5 4
Prothrombin Inhibitor D-leucyl-n-(3-chlorobenzyl)-l-prolinamid... 18 168
Prothrombin Inhibitor D-leucyl-n-(4-carbamimidoylbenzyl)-l-pro... 13 44
72 kDa type IV collagenase and Matrix metalloproteinase-9 Inhi... 40 87
Neuromedin-K receptor Ligand PD-157672 Family 9 37
Cathepsin K and Cathepsin L1 Inhibitor N-benzoyl-phenylalanyl-... 13 77
Melanocortin receptor 3 and Melanocortin receptor 4 Ligand Tic... 11 31
Cathepsin B and Cathepsin S Inhibitor Ac-hphe-leu-ala-leuvsme ... 17 51
Melanocortin receptor 4 and Substance-K receptor Ligand Hoo-ph... 3 19
Histamine H3 receptor Ligand N-benzyl-4-cyclopentylpiperazine-... 3 19
D(2) dopamine receptor and D(3) dopamine receptor Ligand ST-19... 5 27
Sodium-dependent dopamine transporter and Sodium-dependent nor... 28 71
Muscarinic acetylcholine receptor M4 and Muscarinic acetylchol... 20 55
Baculoviral IAP repeat-containing protein 3 and E3 ubiquitin-p... 44 28
Sodium channel protein type 1 subunit alpha and Sodium channel... 4 31
Sodium-dependent serotonin transporter Inhibitor Irindalone Fa... 16 9
Melatonin receptor type 1A Ligand N-(2,3-dihydro-1h-phenalen-2... 8 13
Prolyl endopeptidase Inhibitor SUAM-1221 Family 42 47
Aminopeptidase N Inhibitor 2-cinnamamido-n4-hexyl-n1-hydroxysu... 24 8
Melanocortin receptor 4 and Melanocyte-stimulating hormone rec... 3 10
Substance-P receptor ligand (2S)-N-[(2S)-1-[benzyl(methyl)amin... 5 9
Disintegrin and metalloproteinase domain-containing protein 17... 4 1
B2 bradykinin receptor ligand SureCN13864840 family 1 6
Kappa-type opioid receptor ligand 1-[(2S)-2-(pyrrolidin-1-ylme... 4 0
Dipeptidyl peptidase 4 inhibitor (2S)-1-[(2S,4S,5S)-4-(1,3-dih... 3 14
Dipeptidyl peptidase 4 and Dipeptidyl peptidase 8 inhibitor (2... 5 3
Cathepsin K and Cathepsin S inhibitor 1-benzyl-3-[(2S)-1-[[cya... 1 0
Neuromedin-K receptor ligand SureCN2477089 family 2 4
Muscarinic acetylcholine receptor M3 and Muscarinic acetylchol... 3 0
Sigma non-opioid intracellular receptor 1 ligand (10aS)-2-(2-p... 1 2
Oxytocin receptor and Vasopressin V2 receptor ligand (2R)-2-(2... 4 2
Dipeptidyl peptidase 2 and Dipeptidyl peptidase 4 inhibitor (2... 3 10
Peptide deformylase inhibitor (2S)-N-benzoyl-1-[(2R)-2-(cyclop... 2 2
P2X purinoceptor 7 inhibitor SureCN8516206 family 5 1
P2X purinoceptor 7 inhibitor (4S)-3-methyl-N-[[2-methyl-3-(tri... 3 0
Muscarinic acetylcholine receptor M3 and Muscarinic receptor 3... 3 0
Muscarinic acetylcholine receptor M3 and Muscarinic receptor 3... 1 0
Baculoviral IAP repeat-containing protein 3 and E3 ubiquitin-p... 3 1
Follicle-stimulating hormone receptor ligand N-[[3-[4-[[(2S,5S... 7 0
Angiotensin-converting enzyme inhibitor SureCN7263641 family 2 11
Sodium-dependent noradrenaline transporter and Muscarinic acet... 1 2
Histamine H3 receptor ligand Conessine analogue, 13e family 1 0
Prothrombin inhibitor 1-(2-amino-3,3-diphenylpropanoyl)-N-[(3-... 1 1
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 1 0
Cannabinoid receptor 1 and Fatty-acid amide hydrolase 1 ligand... 2 3
Prolyl endopeptidase inhibitor 3eq9 family 1 0
Smoothened homolog inhibitor N-cyclohexyl-1,3-dioxo-2-[(1S,2R)... 2 0
Cannabinoid receptor 1 ligand 3-butyl-5,5-bis(4-iodophenyl)-2-... 1 1


CFAM Mol ID

External ID

Functional Category

Molecule Name


Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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