CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM3100
Family Name Reverse transcriptase/RNaseH inhibitor 1-(5-cyanopyridin-2-yl)-3-[2-(6-fluoro-2-hydroxy-3-propanoylphenyl)cyclopropyl]urea family
No. of Seeds 5 No. of Other Members 0
Family Centroid CFAMM00343318 Functional Category Bioactive
Superfamily C-C chemokine receptor type 2 and Cytochrome P450 2C9 Binder Superfamily
Class Class 2367

Cousin Family NamesSeedsMembers
Potassium voltage-gated channel subfamily H member 2 Ligand Be... 22 56
Reverse transcriptase/RNaseH inhibitor 1-(5-chloropyridin-2-yl... 3 0


External ID

Functional Category

Molecule Name

CFAMM00343318 CHEMBL132425 Bioactive 1-(5-cyanopyridin-2-yl)-3-[2-(6-fluoro-2-hydroxy-3-propanoylphenyl)cyclopropyl]urea
CFAMM00343317 CHEMBL135105 Bioactive 1-[2-(3-acetyl-6-fluoro-2-hydroxyphenyl)cyclopropyl]-3-(5-cyanopyridin-2-yl)urea
CFAMM00343316 CHEMBL133559 Bioactive 1-[2-(3-acetyl-6-fluoro-2-hydroxyphenyl)cyclopropyl]-3-(5-bromopyridin-2-yl)urea
CFAMM00343320 CHEMBL134278 Bioactive 1-(5-chloropyridin-2-yl)-3-[2-(6-fluoro-2-hydroxy-3-propanoylphenyl)cyclopropyl]urea
CFAMM00343319 CHEMBL134026 Bioactive 1-(5-bromopyridin-2-yl)-3-[2-(6-fluoro-2-hydroxy-3-propanoylphenyl)cyclopropyl]urea

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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