CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM311
Family Name Renin inhibitor (1S,5S)-7-[4-[3-(2-chloro-3,6-difluorophenoxy)propyl]phenyl]-N-cyclopropyl-N-[(2,3-dichlorophenyl)methyl]-3,9-diazabicyclo[3.3.1]non-6-ene-6-carboxamide family
No. of Seeds 11 No. of Other Members 16
Family Centroid CFAMM00310149 Functional Category Bioactive
Superfamily Renin Binder Superfamily 3
Class Class 3124

Cousin Family NamesSeedsMembers
Renin inhibitor (1R,5R)-3-[4-[3-(2-chloro-3,6-difluorophenoxy)... 5 2
Renin inhibitor AGN-PC-07ZC01 family 12 16
Renin inhibitor SureCN1472318 family 4 1
Renin and Cytochrome P450 3A4 inhibitor (3R,4S)-N-[[2-chloro-5... 28 3
Renin inhibitor (1R,5S)-N-[(2-chlorophenyl)methyl]-7-[4-[3-[(2... 9 0
Renin inhibitor (1R,5S)-3-acetyl-N-cyclopropyl-N-[(2,3-dichlor... 11 0
Renin inhibitor SureCN5073976 family 6 0
Renin inhibitor AGN-PC-00CP4L family 2 0
Renin inhibitor 3-(4-amino-4-oxobutanoyl)-N-[(2-chlorophenyl)m... 2 0
Renin inhibitor (1R,5S)-3-acetyl-7-[4-[3-(2-bromo-5-fluorophen... 3 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00310152 CHEMBL500811 Bioactive SureCN4982489
CFAMM00310151 CHEMBL1076449 Bioactive (1R,5R)-3-[4-[3-(2-chloro-3,6-difluorophenoxy)propyl]phenyl]-N-cyclopropyl-N-[(2,3-dichlorophenyl)methyl]-8-azabicyclo[3.2.1]oct-3-ene-4-carboxamide
CFAMM00310137 CHEMBL509903 Bioactive SureCN4983278
CFAMM00310150 CHEMBL1076443 Bioactive (1S,5S)-7-[4-[3-(2-chloro-3,6-difluorophenoxy)propyl]phenyl]-N-cyclopropyl-N-[(2,3-dichlorophenyl)methyl]-3-oxa-9-azabicyclo[3.3.1]non-6-ene-6-carboxamide
CFAMM00310130 CHEMBL454732 Bioactive (1R,5S)-3-acetyl-7-[4-[3-(2-chloro-3,6-difluorophenoxy)propyl]phenyl]-N-cyclopropyl-N-[(2,3-dichlorophenyl)methyl]-3,9-diazabicyclo[3.3.1]non-6-ene-6-carboxamide
CFAMM00310136 CHEMBL1091040 Bioactive AGN-PC-00QPXW
CFAMM00310149 CHEMBL1076442 Bioactive (1S,5S)-7-[4-[3-(2-chloro-3,6-difluorophenoxy)propyl]phenyl]-N-cyclopropyl-N-[(2,3-dichlorophenyl)methyl]-3,9-diazabicyclo[3.3.1]non-6-ene-6-carboxamide
CFAMM00310155 CHEMBL1092756 Bioactive AGN-PC-00QPZP
CFAMM00310148 CHEMBL1076445 Bioactive (1S,5S)-7-[4-[3-(2-chloro-3,6-difluorophenoxy)propyl]phenyl]-N-cyclopropyl-N-[(2,3-dichlorophenyl)methyl]-3,3-dioxo-3$l^{6}-thia-9-azabicyclo[3.3.1]non-6-ene-6-carboxamide
CFAMM00310154 CHEMBL1088290 Bioactive AGN-PC-07Z9L8
CFAMM00310147 CHEMBL1076444 Bioactive (1R,5R)-3-[4-[3-(2-chloro-3,6-difluorophenoxy)propyl]phenyl]-N-cyclopropyl-N-[(2,3-dichlorophenyl)methyl]-9-azabicyclo[3.3.1]non-3-ene-4-carboxamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27284 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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