CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM3128
Family Name Pol polyprotein inhibitor Lysine Sulfonamide 11o family
No. of Seeds 2 No. of Other Members 6
Family Centroid CFAMM00343542 Functional Category Bioactive
Superfamily Aldose reductase Inhibitor Inhibitor Idd 384 Superfamily
Class Class 1779

Cousin Family NamesSeedsMembers
HIV protease Inhibitor Amprenavir Family 7 15
Angiotensin-converting enzyme Inhibitor Benazepril Family 7 123
Integrin alpha-4 Inhibitor BIO-1211 Family 16 83
Aldose reductase Inhibitor Inhibitor Idd 384 Family 1 3
Thymidylate synthase Inhibitor Sp-876 Family 7 117
Carbonic anhydrase 1 and Carbonic anhydrase 2 Inhibitor N-(4-s... 12 92
Integrin beta-3 Inhibitor L-750034 Family 7 38
Cholecystokinin receptor type A Ligand VL-1499 Family 12 133
Protein kinase C eta type and Protein kinase C delta type Inhi... 9 12
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 14 110
Leukotriene A-4 hydrolase Inhibitor SA-6541 Family 4 32
Prothrombin and Plasminogen inhibitor [(1R)-5-amino-1-[[2-[N-(... 1 0
72 kDa type IV collagenase and Collagenase 3 inhibitor SureCN7... 1 8
72 kDa type IV collagenase and Collagenase 3 inhibitor SureCN7... 1 1
Integrin beta-1 and Integrin alpha-4 inhibitor (2S)-2-[[(2S)-1... 6 6
Pol polyprotein inhibitor Lysine Sulfonamide 14a family 12 3
Pol polyprotein inhibitor Lysine Sulfonamide 11t family 1 4
Pol polyprotein inhibitor Lysine Sulfonamide 11c family 3 73
Mitogen-activated protein kinase 1 and M17 leucyl aminopeptida... 1 21
Carbonic anhydrase 2 and Carbonic anhydrase 4 inhibitor AC1MRX... 4 4
Carbonic anhydrase 2 and Carbonic anhydrase 4 inhibitor AGN-PC... 2 0
Carbonic anhydrase 2 and Carbonic anhydrase 4 inhibitor AGN-PC... 2 0
72 kDa type IV collagenase and Stromelysin-1 inhibitor (2R)-N-... 2 7
72 kDa type IV collagenase and Matrix metalloproteinase-9 inhi... 1 1
Stromelysin-1 and 72 kDa type IV collagenase inhibitor (2R)-2-... 2 1
Stromelysin-1 inhibitor 6-(4'-FLUORO-BIPHENYL-4-YL)-4-(3-METHY... 3 0
Pol polyprotein inhibitor AC1LAHQ3 family 13 0
Pol polyprotein and Pepsin A-5 inhibitor Lysine derivative 28 ... 2 10
Pol polyprotein inhibitor AC1LAHBI family 2 1
Kappa-type opioid receptor ligand SureCN5346063 family 4 0
Neprilysin and Angiotensin-converting enzyme inhibitor (2S)-1-... 3 3
Angiotensin-converting enzyme inhibitor 1-[(2R,4R)-4-carboxy-2... 2 3
Caspase-8 and Caspase-3 inhibitor (3S)-3-[[(2S)-4-methyl-2-[[2... 3 2
Integrin beta-1 and Integrin alpha-4 inhibitor (2S)-2-[[4-[2-[... 1 0
Collagenase 3 inhibitor (2R)-2-[1-[(2-methylpropan-2-yl)oxycar... 4 2
Neprilysin and Angiotensin-converting enzyme inhibitor 3-[(3S)... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00343543 CHEMBL132606 Bioactive Lysine Sulfonamide 11s
CFAMM00343542 CHEMBL132548 Bioactive Lysine Sulfonamide 11o

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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