CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM3130
Family Name Calpain-2 catalytic subunit and Calpain-1 catalytic subunit inhibitor AGN-PC-075LAX family
No. of Seeds 1 No. of Other Members 8
Family Centroid CFAMM00343562 Functional Category Bioactive
Superfamily Prothrombin Inhibitor Ximelagatran Superfamily
Class Class 608

Cousin Family NamesSeedsMembers
Vasopressin V1a receptor Ligand Felypressin Family 12 820
Alpha-1B adrenergic receptor Ligand Lisdexamfetamine Family 14 443
Glutathione S-transferase Inhibitor Praziquantel Family 5 167
Melanocortin receptor 4 Ligand Ro-27-3225 Family 6 52
Dipeptidyl peptidase 4 Inhibitor Denagliptin Family 24 151
Prothrombin Inhibitor Ppack Family 5 4
Proto-oncogene tyrosine-protein kinase Src Inhibitor RU83876 F... 3 51
72 kDa type IV collagenase and Matrix metalloproteinase-9 Inhi... 40 87
Plasmepsin-1 Inhibitor SC-5003 Family 93 173
Neuromedin-K receptor Ligand PD-157672 Family 9 37
Melanocortin receptor 3 and Melanocortin receptor 4 Ligand Tic... 11 31
Cathepsin B and Cathepsin S Inhibitor Ac-hphe-leu-ala-leuvsme ... 17 51
Melanocortin receptor 4 and Substance-K receptor Ligand Hoo-ph... 3 19
Baculoviral IAP repeat-containing protein 3 and E3 ubiquitin-p... 44 28
Sodium channel protein type 1 subunit alpha and Sodium channel... 4 31
Prolyl endopeptidase Inhibitor SUAM-1221 Family 42 47
Aminopeptidase N Inhibitor 2-cinnamamido-n4-hexyl-n1-hydroxysu... 24 8
Voltage-dependent calcium channel gamma-1 subunit Ligand NP-11... 8 9
Substance-K receptor ligand (4S)-4-amino-1-[4-(oxan-4-ylmethyl... 1 2
Renin and Cathepsin D inhibitor (2S)-N-[(2S,3R,4S)-1-cyclohexy... 13 2
Growth hormone secretagogue receptor type 1 ligand (E)-5-amino... 2 2
Cathepsin S inhibitor SureCN7062841 family 7 7
Renin and Cathepsin D inhibitor tert-butyl N-[(2S)-1-[[(2S)-1-... 3 4
Melanocortin receptor 4 and Melanocortin receptor 5 ligand (2S... 16 24
Muscarinic acetylcholine receptor M3 and Muscarinic acetylchol... 3 0
Dipeptidyl peptidase 4 inhibitor (3R)-4-[(3R)-3-amino-4-(2,4,5... 6 6
Renin and Cathepsin D inhibitor (4S)-5-cyclohexyl-2,2-difluoro... 16 1
Oxytocin receptor and Vasopressin V2 receptor ligand (2R)-2-(2... 4 2
C-C chemokine receptor type 1 ligand N-[(2R)-1-[4-(4-chlorophe... 2 4
Baculoviral IAP repeat-containing protein 3 and E3 ubiquitin-p... 3 1
Renin inhibitor AGN-PC-076HPD family 1 0
72 kDa type IV collagenase and Stromelysin-1 inhibitor (2R)-2-... 6 0
Renin and Cathepsin D inhibitor (4S)-5-cyclohexyl-2,2-difluoro... 15 0
Renin and Cathepsin D inhibitor N-[(2S)-1-[[(2S)-1-[[(2S)-1-cy... 2 0
Follicle-stimulating hormone receptor ligand N-[[3-[4-[[(2S,5S... 7 0
72 kDa type IV collagenase and Stromelysin-1 inhibitor (2R)-N-... 10 0
Coagulation factor X inhibitor ethyl 2-[[(3S)-3-[[2-[[(2R)-2-(... 4 0
Pepsin A and Renin inhibitor N-[(3R)-1-[[(1S)-1-hydroxy-3-[[(2... 1 0
Melanocortin receptor 4 and Melanocortin receptor 3 ligand (2S... 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00343562 CHEMBL132587 Bioactive AGN-PC-075LAX

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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