CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

Family Name Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor SureCN12786734 family
No. of Seeds 6 No. of Other Members 7
Family Centroid CFAMM00310200 Functional Category Bioactive
Superfamily Histamine H3 receptor and Corticosteroid 11-beta-dehydrogenase isozyme 1 Binder Superfamily
Class Class 2606

Cousin Family NamesSeedsMembers
5-hydroxytryptamine receptor 7 and D(2) dopamine receptor Liga... 3 29
Acetylcholinesterase Inhibitor 1-benzene Sulfonyl-cis-2,6-dime... 1 4
Oxytocin receptor and Vasopressin V1a receptor Ligand 1'-tosyl... 1 7
Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor (1S,5... 2 4
Alpha-2B adrenergic receptor and Alpha-2C adrenergic receptor ... 3 34
C-C chemokine receptor type 5 ligand methyl N-[1-[(3S)-4-[benz... 3 18
Histamine H3 receptor ligand 2-[4-[4-[2-[(2R)-2-methylpyrrolid... 4 11
Histamine H3 receptor and Potassium voltage-gated channel subf... 6 3
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 3 10
Histamine H3 receptor and Potassium voltage-gated channel subf... 5 0
Histamine H3 receptor ligand N,N-diethyl-4-[4-[2-[(2R)-2-methy... 4 0


External ID

Functional Category

Molecule Name

CFAMM00310199 CHEMBL1076580 Bioactive SureCN12786744
CFAMM00310191 CHEMBL1082165 Bioactive (1R,5S)-3-(4-tert-butylphenyl)sulfonyl-8-cyclopentyl-3,8-diazabicyclo[3.2.1]octane
CFAMM00310197 CHEMBL1080752 Bioactive (1S,4S)-2-[4-(2,2-dimethylpropyl)phenyl]sulfonyl-5-methyl-2,5-diazabicyclo[2.2.1]heptane
CFAMM00310189 CHEMBL1081297 Bioactive SureCN12786767
CFAMM00310194 CHEMBL1081453 Bioactive SureCN12786759
CFAMM00310200 CHEMBL1081251 Bioactive SureCN12786734

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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