CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM31533
Family Name Cyclic AMP-dependent transcription factor ATF-1 and Nuclear factor NF-kappa-B p105 subunit inhibitor butyl 3-[[2-chloro-4-(trifluoromethyl)pyrimidine-5-carbonyl]amino]-5-(trifluoromethyl)benzoate family
No. of Seeds 3 No. of Other Members 0
Family Centroid CFAMM00494828 Functional Category Bioactive
Superfamily Nuclear factor NF-kappa-B p105 subunit and Transcription factor AP-1 Binder Superfamily
Class Class 4797

Cousin Family NamesSeedsMembers
Prostaglandin G/H synthase 2 Inhibitor Niflumic Acid Family 7 119
Mitogen-activated protein kinase 8 Inhibitor 2-(2-phenoxypyrim... 12 30
cAMP-specific 3',5'-cyclic phosphodiesterase 4D and cAMP-speci... 3 22


External ID

Functional Category

Molecule Name

CFAMM00494827 CHEMBL134490 Bioactive AGN-PC-00GD43
CFAMM00494826 CHEMBL423153 Bioactive hexyl 3-[[2-chloro-4-(trifluoromethyl)pyrimidine-5-carbonyl]amino]-5-(trifluoromethyl)benzoate
CFAMM00494828 CHEMBL131636 Bioactive butyl 3-[[2-chloro-4-(trifluoromethyl)pyrimidine-5-carbonyl]amino]-5-(trifluoromethyl)benzoate

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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