CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM3164
Family Name Survival motor neuron protein and 15-hydroxyprostaglandin dehydrogenase [NAD(+)] inhibitor CHEMBL1327949 family
No. of Seeds 1 No. of Other Members 35
Family Centroid CFAMM00344001 Functional Category Bioactive
Superfamily Prostaglandin G/H synthase 2 Inhibitor SC-558 Superfamily
Class Class 2952

Cousin Family NamesSeedsMembers
Prostaglandin G/H synthase 2 Inhibitor Celecoxib Family 3 97
Metabotropic glutamate receptor 5 Ligand 3-(3-pyridin-2-yl-pyr... 4 24
5-hydroxytryptamine receptor 6 Ligand 4-(1h-indol-1-ylsulfonyl... 7 79
Carbonic anhydrase 2 and Carbonic anhydrase 9 Inhibitor Quinol... 4 13
5-hydroxytryptamine receptor 6 Ligand 6-tosyl-1,2,3,4,5,6-hexa... 4 22
Carbonic anhydrase 1 and Carbonic anhydrase 2 Inhibitor 4-(met... 4 15
Prostaglandin G/H synthase 2 Inhibitor SC-558 Family 1 2
5-hydroxytryptamine receptor 2A ligand SureCN5215979 family 2 10
Carbonic anhydrase 12 and Carbonic anhydrase 9 inhibitor 4-(4-... 1 0
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 2 6
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 2 0
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 10 0
D(3) dopamine receptor and D(2) dopamine receptor ligand AGN-P... 1 1
Carbonic anhydrase 2 and Carbonic anhydrase 12 inhibitor 5-[1-... 7 5
Glucocorticoid receptor ligand (4aR)-1-(4-fluorophenyl)-4a-(me... 18 2
Glucocorticoid receptor ligand 1-[(4aS)-6-(4-tert-butylphenyl)... 27 3
Glucocorticoid receptor ligand 4-[[(4aS)-6-(4-tert-butylphenyl... 4 0
Glucocorticoid receptor ligand 6-benzyl-1-(4-fluorophenyl)-4a-... 2 0
Prostaglandin G/H synthase 2 and Prostaglandin G/H synthase 1 ... 1 10
Carbonic anhydrase 2 and Carbonic anhydrase 5A, mitochondrial ... 3 3
Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor SureC... 2 1
Carbonic anhydrase 9 and Carbonic anhydrase 12 inhibitor ethyl... 1 0
Prostaglandin G/H synthase 2 and Prostaglandin G/H synthase 1 ... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00343997 CHEMBL1928571 Bioactive 5-cyano-N-[(E)-(5-cyanopyrazolo[1,5-a]pyridin-3-yl)methylideneamino]-N,2-dimethylbenzenesulfonamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27674 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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