CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM3172
Family Name B2 bradykinin receptor ligand (E)-3-[6-(2-oxopyrrolidin-1-yl)pyridin-3-yl]-N-[2-oxo-2-[N,2,4-trimethyl-3-[(2-methylquinolin-8-yl)oxymethyl]anilino]ethyl]prop-2-enamide;dihydrochloride family
No. of Seeds 3 No. of Other Members 2
Family Centroid CFAMM00279372 Functional Category Bioactive
Superfamily B2 bradykinin receptor Binder Superfamily
Class Class 297

Cousin Family NamesSeedsMembers
Receptor tyrosine-protein kinase erbB-2 Inhibitor CP-724714 Fa... 4 180
AP26113 family 16 90
D(2) dopamine receptor and D(3) dopamine receptor Ligand [2-(1... 17 100
B2 bradykinin receptor Ligand FR-173657 Family 44 180
Liver carboxylesterase 1 Inhibitor SM-32504 Family 3 28
Alpha-1B adrenergic receptor and Alpha-1D adrenergic receptor ... 6 35
Tyrosine-protein kinase Lck inhibitor 4-N-(2-chloro-6-methylph... 8 45
Tyrosine-protein kinase JAK2 and Tyrosine-protein kinase JAK1 ... 5 25
Tyrosine-protein kinase Lck inhibitor AGN-PC-073GX8 family 12 1
B2 bradykinin receptor ligand (E)-3-(6-acetamidopyridin-3-yl)-... 1 0
Plasmepsin-2 inhibitor N-[(2S)-1-[[(2S)-6-amino-1-[4-[(6-metho... 5 12
Vascular endothelial growth factor receptor 2 ligand AGN-PC-09... 5 11
B2 bradykinin receptor ligand SureCN8561638 family 30 3
B2 bradykinin receptor ligand SureCN7749611 family 4 1
B2 bradykinin receptor ligand 4-[(E)-3-[[2-[2,4-dichloro-3-[[4... 29 2
B2 bradykinin receptor ligand SureCN7977402 family 5 6
B2 bradykinin receptor ligand SureCN8516699 family 3 2
B2 bradykinin receptor ligand SureCN6640854 family 7 4
D(3) dopamine receptor and D(2) dopamine receptor ligand SureC... 5 4
Neuropeptide Y receptor type 1 ligand 1-[3-[1-(cyclohexylmethy... 15 9
Prostaglandin E2 receptor EP4 subtype ligand AGN-PC-09QHF0 family 3 1
Calcium/calmodulin-dependent protein kinase kinase 2 and Focal... 3 17
Coagulation factor X and Cationic trypsin inhibitor AGN-PC-075... 26 7
Insulin-like growth factor 1 receptor ligand 3qqu family 2 12
Melatonin receptor type 1B and Melatonin receptor type 1A liga... 1 0
Elongation factor 1-alpha 1 and Elongation factor 1-alpha 2 in... 2 0
Insulin receptor and Insulin-like growth factor 1 receptor lig... 17 7
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 10 4
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 5 0
Tyrosine-protein kinase BTK and Tyrosine-protein kinase Lyn in... 5 7
Tyrosine-protein kinase BTK and Tyrosine-protein kinase Lyn in... 1 3
Tyrosine-protein kinase BTK and Tyrosine-protein kinase Lyn in... 3 0
Type-1 angiotensin II receptor and Type-2 angiotensin II recep... 4 29
Epidermal growth factor receptor ligand N-[3-[7-[2-methoxy-4-(... 9 3
Angiopoietin-1 receptor and Vascular endothelial growth factor... 4 6
Tyrosine-protein kinase Lck and Proto-oncogene tyrosine-protei... 4 3
Epidermal growth factor receptor ligand AGN-PC-078X8C family 10 8
B2 bradykinin receptor ligand SureCN7976932 family 2 0
B2 bradykinin receptor ligand (E)-N-[2-[N-methyl-3-[(2-methylq... 2 0
B2 bradykinin receptor ligand 1-N,3-N-dimethyl-4-[methyl-[2-[[... 4 1
Sterol O-acyltransferase 1 inhibitor AGN-PC-07CO2O family 1 0
Acyl-CoA:cholesterol acyltransferase inhibitor SureCN8919280 f... 23 18
Acyl-CoA:cholesterol acyltransferase inhibitor AGN-PC-00FHC0 f... 2 0
Acyl-CoA:cholesterol acyltransferase inhibitor 1-[2-(dimethyla... 2 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00344131 CHEMBL555976 Bioactive (E)-3-(6-acetamidopyridin-3-yl)-N-[[1-[2,4-diacetamido-3-[(2-methylquinolin-8-yl)oxymethyl]phenyl]pyrrol-2-yl]methyl]prop-2-enamide;dihydrochloride
CFAMM00344130 CHEMBL132860 Bioactive SureCN7975569

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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