CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM3186
Family Name Disintegrin and metalloproteinase domain-containing protein 17 inhibitor (3R,4S)-1-(furan-2-carbonyl)-3-N-hydroxy-4-N-[4-(quinolin-4-yloxymethyl)phenyl]piperidine-3,4-dicarboxamide family
No. of Seeds 2 No. of Other Members 1
Family Centroid CFAMM00344221 Functional Category Bioactive with Natural Product
Superfamily 5-hydroxytryptamine receptor 3A and Neuronal acetylcholine receptor subunit alpha-7 Ligand PH-709829 Superfamily
Class Class 918

Cousin Family NamesSeedsMembers
Sodium channel protein type 5 subunit alpha Ligand Dibucaine F... 2 136
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor indole... 28 2712
72 kDa type IV collagenase and Matrix metalloproteinase-9 Inhi... 37 265
von Willebrand factor Inhibitor Auryntricarboxylic Acid (ata) ... 12 81
Adenosine receptor A1 and Adenosine receptor A2a Ligand SB-298... 53 320
5-hydroxytryptamine receptor 1A and Sodium-dependent serotonin... 7 11
Disintegrin and metalloproteinase domain-containing protein 17... 2 8
Acetylcholinesterase and Muscarinic acetylcholine receptor M2 ... 2 7
Histamine H3 receptor ligand AGN-PC-00BG7Z family 11 49
D(3) dopamine receptor and 5-hydroxytryptamine receptor 1A lig... 10 50
Glutamate receptor ionotropic, NMDA 2D and Glutamate receptor ... 2 21
Growth hormone secretagogue receptor type 1 ligand 2-amino-N-[... 3 3
Cathepsin S and Cathepsin K inhibitor N-[(2S)-3-(1-methylcyclo... 2 0
5-hydroxytryptamine receptor 1D and 5-hydroxytryptamine recept... 3 21
Histone deacetylase 6 and Histone deacetylase 1 inhibitor N-hy... 3 2
Disintegrin and metalloproteinase domain-containing protein 17... 13 3
Substance-P receptor ligand 1-[4-(2-methoxyphenyl)piperazin-1-... 11 12
Melanin-concentrating hormone receptor 1 and Melanin-concentra... 12 0
Disintegrin and metalloproteinase domain-containing protein 17... 16 2
Mu-type opioid receptor and Mu-type opioid receptor ligand (3S... 6 2
Proto-oncogene tyrosine-protein kinase receptor Ret and Vascul... 5 14
Disintegrin and metalloproteinase domain-containing protein 17... 5 4
D(2) dopamine receptor and 5-hydroxytryptamine receptor 1A lig... 1 0
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor 3-(2,3-... 2 1
Melatonin receptor type 1B and Melatonin receptor type 1A liga... 3 9
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor CHEMBL4... 6 2
5-hydroxytryptamine receptor 1D and 5-hydroxytryptamine recept... 1 0
Bombesin receptor subtype-3 ligand 2-[[(E)-furan-2-ylmethylide... 2 4


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00344221 CHEMBL132928 Bioactive (3R,4S)-1-(furan-2-carbonyl)-3-N-hydroxy-4-N-[4-(quinolin-4-yloxymethyl)phenyl]piperidine-3,4-dicarboxamide
CFAMM00344225 CHEMBL136353 Bioactive (3R,4S)-1-(furan-2-carbonyl)-3-N-hydroxy-4-N-[4-[(2-methylquinolin-4-yl)oxymethyl]phenyl]piperidine-3,4-dicarboxamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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