CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM3241
Family Name Poly [ADP-ribose] polymerase 1 inhibitor SureCN6202744 family
No. of Seeds 4 No. of Other Members 2
Family Centroid CFAMM00344770 Functional Category Bioactive
Superfamily BIBT986 Superfamily
Class Class 716

Cousin Family NamesSeedsMembers
Vasopressin V1a receptor and Vasopressin V2 receptor Ligand be... 4 301
Tubulin beta chain Inhibitor Mebendazole Family 12 84
Prothrombin Inhibitor Dabigatran Family 7 182
BIBT986 family 7 96
CC-486 family 7 103
Poly [ADP-ribose] polymerase 1 Inhibitor 2-(3'-methoxyphenyl) ... 9 93
Vascular endothelial growth factor receptor 2 Ligand 6-(1h-ben... 2 5
Telomerase reverse transcriptase Inhibitor HOE-33258 Family 10 33
DNA (cytosine-5)-methyltransferase 3B Inhibitor NSC-57893 Family 3 8
Acetylcholinesterase inhibitor SureCN251059 family 2 16
Poly [ADP-ribose] polymerase 1 inhibitor 2-(3-chlorophenyl)-1H... 4 38
Type-1A angiotensin II receptor and Type-1B angiotensin II rec... 2 9
Poly [ADP-ribose] polymerase 1 inhibitor ethyl 4-(4-carbamoyl-... 2 15
Peroxisome proliferator-activated receptor gamma ligand 1-[(4-... 7 29
5-hydroxytryptamine receptor 4 ligand 6-chloro-N-[[1-(2-methyl... 10 19
Adenosine receptor A2a and Adenosine receptor A2b ligand SureC... 2 2
Sodium-dependent serotonin transporter and 5-hydroxytryptamine... 10 14
Histamine H3 receptor and Potassium voltage-gated channel subf... 7 1
Histamine H3 receptor ligand SureCN2878688 family 8 1
Ribosomal protein S6 kinase alpha-3 inhibitor N-(3-ethylimidaz... 2 2
Gastrin/cholecystokinin type B receptor ligand 3-[[5-[2-(1-ada... 9 15
Casein kinase II subunit alpha and Serine/threonine-protein ki... 1 5
Gastrin/cholecystokinin type B receptor ligand 3-[[5-(1-adaman... 2 0
Vascular endothelial growth factor receptor 2 ligand (3Z)-6-fl... 4 3
Platelet-derived growth factor receptor beta and Vascular endo... 5 12
Glycogen synthase kinase-3 beta inhibitor 2-(4-fluorophenyl)-N... 4 2
Urokinase plasminogen activator surface receptor ligand ethyl ... 1 0
cGMP-dependent 3',5'-cyclic phosphodiesterase and cAMP and cAM... 3 0
Melanocortin receptor 4 ligand AGN-PC-076AMO family 17 8
Melanocortin receptor 4 ligand AGN-PC-076AMT family 2 9
5-hydroxytryptamine receptor 4 and 5-hydroxytryptamine recepto... 10 1
Disintegrin and metalloproteinase domain-containing protein 17... 10 4
Alpha-1A adrenergic receptor and Alpha-1B adrenergic receptor ... 3 0
Tyrosine-protein kinase ITK/TSK and Insulin receptor ligand AG... 5 1
Platelet-derived growth factor receptor beta and Fibroblast gr... 10 0
Platelet-derived growth factor receptor beta and Fibroblast gr... 2 1
Poly [ADP-ribose] polymerase 1 inhibitor AGN-PC-077D0D family 3 0
Poly [ADP-ribose] polymerase 1 inhibitor 2-[4-(1,2-oxazol-5-yl... 2 1
Poly [ADP-ribose] polymerase 1 inhibitor 2-[4-(5-sulfanylidene... 1 1
Poly [ADP-ribose] polymerase 1 and Poly [ADP-ribose] polymeras... 4 0
Poly [ADP-ribose] polymerase 1 inhibitor AGN-PC-077DC5 family 2 2
Reverse transcriptase/RNaseH inhibitor AC1LAPCJ family 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00344771 CHEMBL65791 Bioactive SureCN6197512
CFAMM00344770 CHEMBL432146 Bioactive SureCN6202744
CFAMM00344773 CHEMBL133241 Bioactive 2-[4-(hydroxymethyl)phenyl]-1H-benzimidazole-4-carboxamide
CFAMM00344772 CHEMBL337254 Bioactive 2-[3-(hydroxymethyl)phenyl]-1H-benzimidazole-4-carboxamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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