CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM325
Family Name Glycogen synthase kinase-3 beta inhibitor AGN-PC-07ZA5M family
No. of Seeds 4 No. of Other Members 14
Family Centroid CFAMM00310294 Functional Category Bioactive
Superfamily Glycogen synthase kinase-3 beta and TGF-beta receptor type-1 Binder Superfamily
Class Class 3127

Cousin Family NamesSeedsMembers
Peroxisome proliferator-activated receptor gamma Ligand Piogli... 2 29
5-hydroxytryptamine receptor 1A Ligand Sun N4057 Family 2 86
Glycogen synthase kinase-3 beta and Cyclin-dependent kinase 2 ... 5 1
Glycogen synthase kinase-3 beta inhibitor AGN-PC-07Z9PR family 1 0
Potassium voltage-gated channel subfamily H member 2 and Kappa... 5 33
Histamine H3 receptor ligand 3-[4-[3-[(2R)-2-methylpyrrolidin-... 1 5
cAMP-specific 3',5'-cyclic phosphodiesterase 4B and cGMP-inhib... 18 10
NP (s,z)-n'-(1-((6,7-dimethoxy-1-methyl-3,4-dihydroisoquinolin... 1 1
NP N-(2-(3,4-dimethoxyphenyl)-4-oxo-4h-chromen-6-yl)nicotinami... 6 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00310295 CHEMBL1087246 Bioactive AGN-PC-07ZA5N
CFAMM00310294 CHEMBL1087245 Bioactive AGN-PC-07ZA5M
CFAMM00310307 CHEMBL1082010 Bioactive AGN-PC-07ZA1G
CFAMM00310313 CHEMBL1076721 Bioactive 5-(4-methoxyphenyl)-4-(2-pyridin-3-ylhydrazinyl)pyrazol-3-one

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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