CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM3253
Family Name Sodium/iodide cotransporter inhibitor (3-methoxyphenyl)methyl 4-(furan-2-yl)-6-methyl-2-oxo-3,4-dihydro-1H-pyrimidine-5-carboxylate family
No. of Seeds 4 No. of Other Members 12
Family Centroid CFAMM00344848 Functional Category Bioactive with Natural Product
Superfamily Sodium/iodide cotransporter and Huntingtin Binder Superfamily
Class Class 3764

Cousin Family NamesSeedsMembers
Histamine H3 receptor Ligand A-317920 Family 9 240
Fatty-acid amide hydrolase 1 Inhibitor Furan-2-ylmethylcarbami... 1 105
Sodium-dependent dopamine transporter Inhibitor (+/-)-threo-n-... 4 62
Prostaglandin E2 receptor EP4 subtype ligand SureCN5653729 family 3 2
Sodium/iodide cotransporter inhibitor 1,3-benzodioxol-5-ylmeth... 4 0
Glutamate carboxypeptidase 2 inhibitor (2S)-2-[[(1S)-1-carboxy... 1 0
Matrix metalloproteinase-9 and Interstitial collagenase inhibi... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00344850 CHEMBL2333516 Bioactive (3-methoxyphenyl)methyl 4-(furan-2-yl)-1,3,6-trimethyl-2-oxo-4H-pyrimidine-5-carboxylate
CFAMM00344848 CHEMBL2333514 Bioactive (3-methoxyphenyl)methyl 4-(furan-2-yl)-6-methyl-2-oxo-3,4-dihydro-1H-pyrimidine-5-carboxylate
CFAMM00344853 CHEMBL2333513 Bioactive (4-methoxyphenyl)methyl 4-(furan-2-yl)-1,3,6-trimethyl-2-oxo-4H-pyrimidine-5-carboxylate
CFAMM00344851 CHEMBL2333511 Bioactive (4-methoxyphenyl)methyl 4-(furan-2-yl)-6-methyl-2-oxo-3,4-dihydro-1H-pyrimidine-5-carboxylate

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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