CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM3309
Family Name Calpain-2 catalytic subunit and Calpain-1 catalytic subunit inhibitor benzyl N-[1-[[1-(3-imidazol-1-ylpropylamino)-1,2-dioxopentan-3-yl]amino]-4-methyl-1-oxopentan-2-yl]carbamate family
No. of Seeds 1 No. of Other Members 7
Family Centroid CFAMM00345445 Functional Category Bioactive
Superfamily Integrin beta-3 and Integrin alpha-V Binder Superfamily 11
Class Class 3779

Cousin Family NamesSeedsMembers
Renin Inhibitor Remikiren Family 100 126
Renin Inhibitor Enalkiren Family 56 44
Renin Inhibitor (h-261)boc-his-pro-phe-his-leu(oh)-val-ile-his... 33 41
Cathepsin B and Cathepsin K Inhibitor Z-ala-leu-his-agly-ile-v... 3 2
Pol polyprotein inhibitor propan-2-yl N-[(2S)-1-[[(2S,3S,5R)-3... 6 2
Renin inhibitor tert-butyl N-[(2S)-1-[[(2S)-1-[[(1R,2S)-3-cycl... 3 0
Integrin beta-3 and Integrin alpha-V inhibitor (3R)-4-[4-[3-(1... 2 1
Cathepsin K and Cathepsin L1 inhibitor dipeptidyl nitrile, 16g... 1 0
Glutamate receptor ionotropic, NMDA 2B and Cytochrome P450 2D6... 1 0
Pol polyprotein inhibitor 162540-49-0 family 1 2
Growth hormone secretagogue receptor type 1 ligand Tetrazole-b... 1 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00345445 CHEMBL133634 Bioactive benzyl N-[1-[[1-(3-imidazol-1-ylpropylamino)-1,2-dioxopentan-3-yl]amino]-4-methyl-1-oxopentan-2-yl]carbamate

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27426 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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