CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM3324
Family Name Retinoic acid receptor alpha and Retinoic acid receptor beta ligand 4-[5-(5,5,8,8-tetramethyl-6,7-dihydroquinoxalin-2-yl)-1H-pyrrol-2-yl]benzoic acid family
No. of Seeds 1 No. of Other Members 2
Family Centroid CFAMM00288229 Functional Category Bioactive
Superfamily NS5B protein and Retinoic acid receptor alpha Binder Superfamily
Class Class 3380

Cousin Family NamesSeedsMembers
5-hydroxytryptamine receptor 1B and 5-hydroxytryptamine recept... 14 2769
5-hydroxytryptamine receptor 3A Ligand Dolasetron Family 12 171
Histone deacetylase 1 Inhibitor MS-275 Family 4 41
Dihydroorotate dehydrogenase Inhibitor Brequinar Family 9 122
Dihydroorotate dehydrogenase Inhibitor Cinchoninic Acid Family 1 21
Substance-K receptor and Substance-P receptor Ligand L-732138 ... 8 147
Tyrosine-protein phosphatase non-receptor type 1 Ligand Cauler... 2 8
Lethal factor Inhibitor 3-(2,5-dimethyl-1h-pyrrol-1-yl)benzoic... 2 44
D(2) dopamine receptor and D(3) dopamine receptor Ligand D-366... 5 75
Kinesin-like protein KIF11 Inhibitor Methyl 7-tert-butyl-9h-ca... 2 9
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 24 64
Endothelin B receptor Ligand IRL-2500 Family 34 87
Vasopressin V2 receptor Ligand YM-35278 Family 33 38
Prostaglandin E2 receptor EP4 subtype and Prostaglandin D2 rec... 8 17
Sodium-dependent serotonin transporter and D(2) dopamine recep... 13 2
NS5B protein inhibitor AC1NQMYG family 6 12
Retinoic acid receptor gamma and Retinoic acid receptor alpha ... 2 3
Cannabinoid receptor 2 ligand [(4R,4aS,8aR)-4-hydroxy-4-phenyl... 2 41
cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-speci... 4 4
Acetylcholinesterase inhibitor CHEMBL1651140 family 4 4
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand [(4S,... 5 2
NS5B protein inhibitor AC1NQMYP family 5 0
Prostaglandin D2 receptor 2 ligand 2-[1-(4-benzamidobenzoyl)is... 4 9
Egl nine homolog 1 inhibitor 2-[5-methyl-6-[[1-oxo-2-(4-phenyl... 4 3
Hydroxycarboxylic acid receptor 2 and Cytochrome P450 2C9 liga... 2 6
Rho-associated protein kinase 2 inhibitor 2-hydroxyethyl 3-[2-... 2 0
Beta-3 adrenergic receptor ligand SureCN5704018 family 4 1
Peroxisome proliferator-activated receptor delta and Peroxisom... 2 5
Serine/threonine-protein kinase Sgk1 inhibitor SureCN3774571 f... 2 18
MAP kinase-activated protein kinase 2 inhibitor SureCN14188371... 1 0
TGF-beta receptor type-1 ligand Methyl 4-(4-(3-(pyridin-2-yl)-... 1 2
Serine/threonine-protein kinase pim-3 inhibitor methyl 6-amino... 1 2
Calcium/calmodulin-dependent protein kinase type II subunit de... 1 0
Putative NP ZINC15919780 Family 2 0
2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indol-2-ium-8-carboxylate N... 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name


Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27043 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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