CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM33584
Family Name Beta-lactamase and Histone-lysine N-methyltransferase 2A inhibitor CHEMBL1363687 family
No. of Seeds 1 No. of Other Members 7
Family Centroid CFAMM00500417 Functional Category Bioactive with Natural Product
Superfamily Peroxisome proliferator-activated receptor gamma and Peroxisome proliferator-activated receptor alpha Ligand KRP-297 Superfamily
Class Class 216

Cousin Family NamesSeedsMembers
Sodium channel protein type 5 subunit alpha Ligand Flecainide ... 2 162
Zucapsacin family 7 177
Serine/threonine-protein kinase PLK1 Inhibitor On 019190.na Fa... 16 138
Growth hormone secretagogue receptor type 1 Ligand TZP-101 Family 28 263
Substance-P receptor Ligand Ezlopitant Family 10 207
A disintegrin and metalloproteinase with thrombospondin motifs... 7 119
Potassium voltage-gated channel subfamily H member 2 and Sodiu... 33 83
C-C chemokine receptor type 5 Ligand E-913 Family 6 44
Plasmepsin-2 Inhibitor KNI-727 Family 3 37
Voltage-dependent L-type calcium channel Ligand PD173212 Family 24 104
Cathepsin F Inhibitor Benzoyl-tyrosine-alanine-methyl Ketone F... 34 55
Disintegrin and metalloproteinase domain-containing protein 17... 25 36
Potassium voltage-gated channel subfamily A member 3 Ligand 2-... 9 92
Cannabinoid receptor 1 Ligand N-(4-methoxyphenethyl)oleamide F... 10 36
72 kDa type IV collagenase and Matrix metalloproteinase-9 Inhi... 9 12
Melanin-concentrating hormone receptor 1 Ligand N-(1-benzylpip... 9 57
Voltage-dependent T-type calcium channel subunit alpha-1H Liga... 5 26
Acetylcholinesterase and Cholinesterase Inhibitor Caproctamine... 7 17
Oxytocin receptor Ligand [mpa1, D-tyr(et)2, D-tic7]ot Family 43 26
Matrix metalloproteinase-9 and Collagenase 3 inhibitor 4-benzy... 10 32
Substance-P receptor ligand N-[1-[acetyl-[(2-methoxyphenyl)met... 3 9
Neutrophil elastase inhibitor phenyl N-[(2S)-1-[(2S)-2-[[(3S)-... 10 4
Neutrophil elastase inhibitor (2S)-N-[(3S)-6-benzamido-5,5-dif... 6 10
Neprilysin and Angiotensin-converting enzyme inhibitor AGN-PC-... 3 7
3-hydroxyacyl-CoA dehydrogenase type-2 and Retinal dehydrogena... 1 15
Substance-P receptor ligand AGN-PC-075NP5 family 4 8
Stromelysin-1 and Matrix metalloproteinase-9 inhibitor AGN-PC-... 26 12
Growth hormone secretagogue receptor type 1 ligand 2-benzylsul... 2 0
Angiotensin-converting enzyme and Neprilysin inhibitor (2S,5R)... 15 3
Cathepsin K and Cathepsin S inhibitor (1R,2R)-N-[cyano-(2-meth... 1 0
Baculoviral IAP repeat-containing protein 3 and E3 ubiquitin-p... 7 1
Integrin beta-1 and Integrin alpha-4 inhibitor (2S)-3-[4-(2-me... 4 0
Sodium-dependent serotonin transporter and Sodium-dependent no... 2 11
Sigma non-opioid intracellular receptor 1 ligand (1R,5S)-9-[(4... 3 2
Substance-P receptor ligand (2S)-N-[(2S)-1-[benzyl(methyl)amin... 2 2
Voltage-dependent N-type calcium channel subunit alpha-1B liga... 3 0
Voltage-dependent N-type calcium channel subunit alpha-1B liga... 4 0
Reverse transcriptase/RNaseH inhibitor Thiazoloisoindol-5-one ... 1 2
NP N-(2-methoxyphenethyl)-5-((3as,4s,6ar)-2-oxohexahydro-1h-th... 2 0
(2S)-2-[(2-methoxyphenyl)methylcarbamoylamino]-4-methylsulfany... 3 1
2-[(1R,4aS,8aS)-4a-hydroxy-1-(4-methoxyphenyl)-2,3,4,5,6,7,8,8... 1 0
3,3-dimethyl-7-oxo-6-[[1-(2-propan-2-yloxyphenyl)cyclobutaneca... 8 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00500419 CHEMBL65110 Bioactive SureCN5361976

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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