CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM3410
Family Name 5-hydroxytryptamine receptor 2A ligand AGN-PC-075LXD family
No. of Seeds 4 No. of Other Members 4
Family Centroid CFAMM00346308 Functional Category Bioactive
Superfamily D(2) dopamine receptor and D(3) dopamine receptor Binder Superfamily 17
Class Class 2707

Cousin Family NamesSeedsMembers
Mu-type opioid receptor Ligand Fentanyl Family 9 647
Voltage-dependent T-type calcium channel subunit alpha-1H liga... 10 397
Noradrenergic re-uptake inhibitor Dibenzazepine Imipramine Family 8 178
Motilin receptor Ligand GSK962040 Family 30 457
Potassium voltage-gated channel subfamily A member 3 Ligand CP... 4 26
3-oxo-5-alpha-steroid 4-dehydrogenase 1 Inhibitor 1-methyl-5-(... 6 17
Progesterone receptor Ligand 2,2,4-trimethyl-6-phenyl-1,2-dihy... 5 82
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 9 67
Histamine H3 receptor Ligand (r)-1-(4-nitrophenethyl)-2-methyl... 16 38
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 5 47
Sodium-dependent dopamine transporter and Sodium-dependent nor... 6 42
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 5 18
D(4) dopamine receptor and Alpha-1B adrenergic receptor ligand... 7 27
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 2 1
Sigma non-opioid intracellular receptor 1 ligand 1-[4-[1-adama... 4 23
Sigma non-opioid intracellular receptor 1 ligand 1-[(3-nitroph... 4 2
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand N-[[4... 7 11
Substance-P receptor ligand (2R,3R)-2-benzhydryl-N-(2-iodophen... 2 0
Sigma non-opioid intracellular receptor 1 and Sodium-dependent... 2 1
Cholinesterase inhibitor 10-[[(1R,9aR)-2,3,4,6,7,8,9,9a-octahy... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00346310 CHEMBL134351 Bioactive AGN-PC-075M4J
CFAMM00346309 CHEMBL134423 Bioactive 1-[1,1-bis(4-fluorophenyl)silolan-3-yl]-4-phenylpiperazine
CFAMM00346308 CHEMBL135898 Bioactive AGN-PC-075LXD
CFAMM00346307 CHEMBL337226 Bioactive AGN-PC-075LX9

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

24517 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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