CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM3413
Family Name DNA-(apurinic or apyrimidinic site) lyase and Ras-related protein Rab-9A inhibitor CHEMBL1343627 family
No. of Seeds 1 No. of Other Members 5
Family Centroid CFAMM00346332 Functional Category Bioactive
Superfamily Ras-related protein Rab-9A and Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform Binder Superfamily
Class Class 3394

Cousin Family NamesSeedsMembers
Corticotropin-releasing factor receptor 1 Ligand CRF-1 Antagon... 29 421
Hepatocyte growth factor receptor Ligand Amg 208 Family 20 236
Ibrutinib family 2 27
Tyrosine kinase Inhibitor PKI166 Family 17 198
Cyclin-dependent kinase 2 and Cyclin-dependent kinase 4 Inhibi... 19 48
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 2 7
Corticotropin-releasing factor receptor 1 Ligand BMS-561388 Fa... 10 16
Sodium channel protein type 5 subunit alpha Ligand Enecadin Fa... 1 11
AMP-activated protein kinase Inhibitor 4-(3-bromopyrazolo[1,5-... 1 8
Adenosine receptor A1 and Adenosine receptor A2a ligand NSC658... 8 54
Serine/threonine-protein kinase B-raf inhibitor SureCN1015955 ... 17 18
Serine/threonine-protein kinase B-raf inhibitor 3-[7-[4-[[(3R)... 6 7
Epidermal growth factor receptor and Tyrosine-protein kinase A... 4 3
Epidermal growth factor receptor and Cyclin-dependent kinase 1... 3 4
Proto-oncogene tyrosine-protein kinase Src and Phosphatidylino... 4 20
Serine/threonine-protein kinase Chk2 and Serine/threonine-prot... 3 6
Adenosine receptor A3 and Adenosine receptor A2a ligand 4-(5-b... 2 5
Tyrosine-protein kinase HCK and Proto-oncogene tyrosine-protei... 5 9
Proto-oncogene tyrosine-protein kinase Src and Tyrosine-protei... 12 8
Translocator protein inhibitor AGN-PC-080ILF family 9 3
Cellular tumor antigen p53 inhibitor CHEMBL1401545 family 1 25
Gamma-aminobutyric acid receptor subunit pi and GABA theta sub... 4 4
Type-1A angiotensin II receptor and Type-1B angiotensin II rec... 1 0
Cellular tumor antigen p53 and Microtubule-associated protein ... 1 6
Tyrosine-protein kinase JAK2 inhibitor 5-(3-methoxyphenyl)-N-[... 2 11
Prostaglandin D2 receptor ligand 2-methoxy-N-[2-(4-methoxyphen... 2 5
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 1 17
Gamma-aminobutyric acid receptor subunit gamma-2 and Gamma-ami... 7 6
Calmodulin-domain protein kinase 1 and Tyrosine-protein kinase... 5 5
Hepatocyte growth factor receptor ligand 4-[(6-phenyl-[1,2,4]t... 3 6
Receptor-type tyrosine-protein kinase FLT3 and Mast/stem cell ... 1 6
Serine/threonine-protein kinase pim-2 and Serine/threonine-pro... 2 3
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 6 0
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 4 4
cGMP-dependent 3',5'-cyclic phosphodiesterase and cAMP and cAM... 3 0
Estrogen receptor and Estrogen receptor beta ligand 4-[3-[4-(2... 1 0
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 2 5
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 3 1
Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor 4-[4-... 1 0
Type-1 angiotensin II receptor ligand 2-ethyl-6-methoxy-N-[[4-... 2 0
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 2 2
Gamma-aminobutyric acid receptor subunit pi and GABA theta sub... 4 3
Adenosine receptor A1 and Adenosine receptor A2a ligand 7-meth... 2 0
Adenosine receptor A2a ligand AGN-PC-077RYH family 16 5
Adenosine receptor A2a ligand AGN-PC-077RYF family 3 0
Hepatocyte growth factor receptor ligand AGN-PC-077K0V family 3 0
Hepatocyte growth factor receptor ligand 4-[(6-thiophen-2-yl-[... 4 0
Aurora kinase A and Glycogen synthase kinase-3 beta inhibitor ... 1 2
Serine/threonine-protein kinase B-raf inhibitor AGN-PC-07CQG5 ... 2 1
Delta-type opioid receptor and 5-hydroxytryptamine receptor 7 ... 1 6
Gamma-aminobutyric acid receptor subunit pi and GABA theta sub... 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00346342 CHEMBL338057 Bioactive AGN-PC-01MMUS

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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