CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM3437
Family Name Androgen receptor ligand (6R,7R)-6,7-diethyl-4-(trifluoromethyl)-6,7,8,9-tetrahydropyrano[3,2-g]quinolin-2-one family
No. of Seeds 15 No. of Other Members 20
Family Centroid CFAMM00346687 Functional Category Bioactive with Natural Product
Superfamily Progesterone receptor and Androgen receptor Binder Superfamily 2
Class Class 761

Cousin Family NamesSeedsMembers
D(4) dopamine receptor Ligand PD-165167 Family 2 96
Amine oxidase [flavin-containing] A Inhibitor Ethyl 4-(2-oxo-2... 4 117
Peptidyl-prolyl cis-trans isomerase A Inhibitor 7-amino-4-meth... 4 59
Amine oxidase [flavin-containing] B Inhibitor N-methyl-n-pheny... 6 25
Galanin receptor type 1 and Galanin receptor type 2 Ligand Gal... 55 132
Fatty-acid amide hydrolase 1 Inhibitor Phenmedipham Family 2 5
Acetylcholinesterase Inhibitor 6-methyl-4-(4-phenylpiperazin-1... 6 622
Neuropeptide S receptor and Prelamin-A/C ligand CHEMBL1352632 ... 1 25
Acetylcholinesterase inhibitor trimethyl-(2-methyl-3-propanoyl... 3 2
Acetylcholinesterase inhibitor AGN-PC-075N8G family 2 9
D(4) dopamine receptor and D(3) dopamine receptor ligand 3-ben... 5 334
Androgen receptor ligand 10-(hydroxymethyl)-4-methyl-1,5-dihyd... 2 2
Progesterone receptor ligand 7-(diethylamino)-6-(4-nitrophenyl... 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00346687 CHEMBL2052002 Bioactive (6R,7R)-6,7-diethyl-4-(trifluoromethyl)-6,7,8,9-tetrahydropyrano[3,2-g]quinolin-2-one
CFAMM00346665 CHEMBL6721 Bioactive 6,8-diethyl-4-(trifluoromethyl)-6,7,8,9-tetrahydropyrano[3,2-g]quinolin-2-one
CFAMM00346671 CHEMBL269305 Bioactive AGN-PC-0743RZ
CFAMM00346685 CHEMBL266928 Bioactive AGN-PC-0743TW
CFAMM00346669 CHEMBL268098 Bioactive Coumarin 340
CFAMM00346689 CHEMBL266473 Bioactive 8-ethyl-4-(trifluoromethyl)-6,7,8,9-tetrahydropyrano[3,2-g]quinolin-2-one

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26816 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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