CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM3467
Family Name Pol polyprotein inhibitor Lysine Sulfonamide 14a family
No. of Seeds 12 No. of Other Members 3
Family Centroid CFAMM00346887 Functional Category Bioactive
Superfamily HIV protease Inhibitor Amprenavir Superfamily
Class Class 136

Cousin Family NamesSeedsMembers
HIV protease Inhibitor Amprenavir Family 7 15
Integrin beta-3 Inhibitor L-750034 Family 7 38
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 14 110
Ileal sodium/bile acid cotransporter inhibitor (4R,5R)-5-(3-am... 2 24
72 kDa type IV collagenase and Matrix metalloproteinase-9 inhi... 12 49
Integrin beta-1 and Integrin alpha-4 inhibitor (2S)-2-[[(2S)-1... 6 6
Pol polyprotein inhibitor Lysine Sulfonamide 11o family 2 6
Pol polyprotein inhibitor Lysine Sulfonamide 11c family 3 73
Carbonic anhydrase 2 and Carbonic anhydrase 4 inhibitor AGN-PC... 2 0
Pol polyprotein inhibitor AC1LAHQ3 family 13 0
Pol polyprotein and Pepsin A-5 inhibitor Lysine derivative 28 ... 2 10
Pol polyprotein inhibitor AC1LAHBI family 2 1
Kappa-type opioid receptor ligand SureCN5346063 family 4 0
Pol polyprotein inhibitor SureCN4637317 family 19 6
Pol polyprotein inhibitor SureCN4782454 family 5 3
Collagenase 3 and Neutrophil collagenase inhibitor (2R)-2-[ben... 2 12
Microbial collagenase inhibitor AGN-PC-074HKS family 4 3
Neutrophil collagenase and Matrix metalloproteinase-9 inhibito... 4 1
Neutrophil collagenase and 72 kDa type IV collagenase inhibito... 10 3
Matrix metalloproteinase-9 and Neutrophil collagenase inhibito... 7 0
Neutrophil collagenase and 72 kDa type IV collagenase inhibito... 3 0
72 kDa type IV collagenase and Neutrophil collagenase inhibito... 2 2
Ileal sodium/bile acid cotransporter inhibitor 2-[[2-[3-[(4R,5... 2 0
Matrix metalloproteinase-9 and Neutrophil collagenase inhibito... 2 0
Microbial collagenase inhibitor AGN-PC-00F1J7 family 4 2
Microbial collagenase inhibitor AGN-PC-074HB8 family 3 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00346897 CHEMBL136546 Bioactive AC1LAGJX
CFAMM00346890 CHEMBL135165 Bioactive Lysine Sulfonamide 13a
CFAMM00346896 CHEMBL337537 Bioactive AC1LAGKC
CFAMM00346889 CHEMBL433883 Bioactive Lysine Sulfonamide 14l
CFAMM00346895 CHEMBL137139 Bioactive AC1LAGJU
CFAMM00346901 CHEMBL137511 Bioactive AC1LAGJR
CFAMM00346894 CHEMBL136051 Bioactive AC1LAGKI
CFAMM00346887 CHEMBL134735 Bioactive Lysine Sulfonamide 14a
CFAMM00346893 CHEMBL422458 Bioactive Lysine Sulfonamide 14k
CFAMM00346899 CHEMBL135429 Bioactive AC1LAGKF
CFAMM00346892 CHEMBL342152 Bioactive Lysine Sulfonamide 13j
CFAMM00346898 CHEMBL343709 Bioactive Lysine Sulfonamide 14j

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27281 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543