CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

Family Name Pol polyprotein inhibitor penicillin deriv. 34 family
No. of Seeds 3 No. of Other Members 18
Family Centroid CFAMM00310643 Functional Category Bioactive with Natural Product
Superfamily Pol polyprotein and Matrix metalloproteinase-9 Binder Superfamily 2
Class Class 2530

Cousin Family NamesSeedsMembers
Vasopressin V1a receptor Ligand Felypressin Family 12 820
Cathepsin K and Cathepsin L1 Inhibitor N-benzoyl-phenylalanyl-... 13 77
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 3 21
Substance-P receptor Ligand [sar9,met(o2)11]-sp Family 34 9
Pol polyprotein inhibitor penicillin deriv. 49 family 3 19
Pol polyprotein inhibitor penicillin deriv. 38 family 1 1
Dipeptidyl peptidase 4 and Dipeptidyl peptidase 8 inhibitor (2... 5 3
Matrix metalloproteinase-9 and 72 kDa type IV collagenase inhi... 1 162
Sodium-dependent noradrenaline transporter and Sodium-dependen... 5 5
Pol polyprotein inhibitor penicillin deriv. 43 family 2 1
Retinal dehydrogenase 1 and 15-hydroxyprostaglandin dehydrogen... 2 0
Reverse transcriptase/RNaseH inhibitor (R)-(+)9B-(3-METHYL)PHE... 5 24


External ID

Functional Category

Molecule Name

CFAMM00310643 CHEMBL107748 Bioactive penicillin deriv. 34
CFAMM00310634 CHEMBL274534 Bioactive penicillin deriv. 44
CFAMM00310640 CHEMBL323318 Bioactive (2R)-2-[(1R)-2-(ethylamino)-2-oxo-1-[(2-phenylbenzoyl)amino]ethyl]-N-[2-[[(2R,4S)-2-[(1R)-2-(ethylamino)-2-oxo-1-[(2-phenylbenzoyl)amino]ethyl]-5,5-dimethyl-1,3-thiazolidine-4-carbonyl]amino]ethyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxamide

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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