CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM3521
Family Name Type-1 angiotensin II receptor and Type-2 angiotensin II receptor ligand SureCN9308798 family
No. of Seeds 6 No. of Other Members 44
Family Centroid CFAMM00347367 Functional Category Bioactive
Superfamily C-C chemokine receptor type 5 and Type-1 angiotensin II receptor Binder Superfamily
Class Class 2341

Cousin Family NamesSeedsMembers
Type-1 angiotensin II receptor Ligand Candesartan Family 3 75
Type-1 angiotensin II receptor Ligand Telmisartan Family 4 181
Type-1 angiotensin II receptor Ligand Eprosartan Family 36 176
Integrin alpha-4 Inhibitor CDP323 Family 8 17
Prostaglandin G/H synthase 2 Inhibitor RWJ-67657 Family 3 33
Thromboxane-A synthase Inhibitor CGS-13080 Family 3 19
RAF proto-oncogene serine/threonine-protein kinase Inhibitor L... 219 124
Type-2 angiotensin II receptor Ligand L-158282 Family 24 58
Type-1 angiotensin II receptor and Type-2 angiotensin II recep... 6 8
Acetylcholinesterase inhibitor SureCN251059 family 2 16
Bombesin receptor subtype-3 ligand AGN-PC-07ZAKV family 13 23
Thromboxane-A synthase inhibitor AGN-PC-00N7V2 family 3 6
3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitor AC1O... 18 10
Type-1 angiotensin II receptor and Type-2 angiotensin II recep... 16 34
Type-1 angiotensin II receptor ligand SureCN9527437 family 2 34
Type-1A angiotensin II receptor and Type-1B angiotensin II rec... 2 9
Survival motor neuron protein and Menin inhibitor CHEMBL132797... 1 1
C-C chemokine receptor type 5 ligand AC1LA25C family 3 6
C-C chemokine receptor type 5 ligand (2R)-3-cyclobutyl-2-[(3S,... 9 4
D(4) dopamine receptor and D(2) dopamine receptor ligand 4-met... 13 8
Carboxypeptidase B2 and Carboxypeptidase B inhibitor 3-(6-amin... 5 10
Nuclear receptor ROR-gamma and Mitogen-activated protein kinas... 1 10
Prostaglandin D2 receptor 2 ligand SureCN2215286 family 7 5
Melanin-concentrating hormone receptor 1 ligand SureCN3334191 ... 4 7
Cytochrome P450 26A1 and Cytochrome P450 3A4 inhibitor AGN-PC-... 5 17
A disintegrin and metalloproteinase with thrombospondin motifs... 1 3
C-C chemokine receptor type 5 ligand SureCN13543564 family 10 3
5-hydroxytryptamine receptor 3A and 5-hydroxytryptamine recept... 9 6
C-C chemokine receptor type 5 and Potassium voltage-gated chan... 11 0
Type-1 angiotensin II receptor and Type-2 angiotensin II recep... 6 5
Type-1A angiotensin II receptor ligand 2-[[2-butyl-3-[(4-carbo... 2 4
C-C chemokine receptor type 5 ligand AC1MHRXO family 5 1
C-C chemokine receptor type 5 ligand (2R)-3-cyclobutyl-2-[(3S,... 2 0
Type-1 angiotensin II receptor and Type-1A angiotensin II rece... 3 0
Integrin beta-3 and Integrin alpha-V inhibitor AGN-PC-00IW9E f... 3 0
Type-1 angiotensin II receptor and Type-2 angiotensin II recep... 9 2
Type-1 angiotensin II receptor and Type-2 angiotensin II recep... 3 0
Diacylglycerol O-acyltransferase 1 inhibitor 2-[4-[4-[5-(6-chl... 2 0
Type-1A angiotensin II receptor and Type-1B angiotensin II rec... 3 6
Type-1 angiotensin II receptor and Type-2 angiotensin II recep... 1 3
Type-1 angiotensin II receptor ligand SureCN7390271 family 2 1
Integrin alpha-4 inhibitor (2S)-2-[(2-bromo-3-oxospiro[3.5]non... 9 0
Type-1A angiotensin II receptor ligand 2-[4-[[2-butyl-5-(tert-... 1 0
Serine/threonine-protein kinase Sgk1 inhibitor SureCN3774571 f... 2 18
Integrin beta-1 and Integrin alpha-5 inhibitor (2S)-3-[4-[4-[[... 2 0
A disintegrin and metalloproteinase with thrombospondin motifs... 1 1
Type-1B angiotensin II receptor ligand SureCN9310003 family 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00347367 CHEMBL135089 Bioactive SureCN9308798
CFAMM00347392 CHEMBL336738 Bioactive SureCN9307461
CFAMM00347350 CHEMBL135346 Bioactive SureCN9308600
CFAMM00347383 CHEMBL335289 Bioactive 2-[N-ethyl-4-[(2-ethyl-5,7-dimethylimidazo[4,5-b]pyridin-3-yl)methyl]-2-methylanilino]-2-phenylacetic acid
CFAMM00347349 CHEMBL135345 Bioactive SureCN9307861

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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