CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM353
Family Name 5-hydroxytryptamine receptor 1D and 5-hydroxytryptamine receptor 1B ligand (E)-but-2-enedioic acid;[4-chloro-3-(4-methylpiperazin-1-yl)phenyl] 4-(2-methylphenyl)piperazine-1-carboxylate family
No. of Seeds 2 No. of Other Members 10
Family Centroid CFAMM00310689 Functional Category Bioactive
Superfamily 5-hydroxytryptamine receptor 1D and 5-hydroxytryptamine receptor 1B ligand (E)-but-2-enedioic acid;[4-chloro-3-(4-methylpiperazin-1-yl)phenyl] 4-(2-methylphenyl)piperazine-1-carboxylate Superfamily
Class Class 217

Cousin Family NamesSeedsMembers
D(2) dopamine receptor ligand phenylpiperazine derivative Arip... 3 53
5-hydroxytryptamine receptor 1A Ligand (s)-way 100135 Family 94 975
C-C chemokine receptor type 1 Ligand BX-471 Family 10 67
5-hydroxytryptamine receptor 1A Ligand NAN-190 Family 14 28
Macrophage migration inhibitory factor Inhibitor 3-benzyl-5-me... 10 42
5-hydroxytryptamine receptor 1A and Sodium-dependent dopamine ... 9 79
Galanin receptor type 1 and Galanin receptor type 2 Ligand Gal... 55 132
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 9 28
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 21 13
Liver carboxylesterase 1 Inhibitor SCH-48375 Family 2 28
D(4) dopamine receptor and D(2) dopamine receptor ligand 2-[4-... 2 6
D(4) dopamine receptor and D(2) dopamine receptor ligand AGN-P... 2 1
Substance-P receptor ligand N-[1-[acetyl-[(2-methoxyphenyl)met... 3 9
D(3) dopamine receptor and D(2) dopamine receptor ligand 1-(3-... 4 6
D(4) dopamine receptor and D(2) dopamine receptor ligand 1-(4-... 3 5
Delta-type opioid receptor and Mu-type opioid receptor ligand ... 9 0
Neuropeptide S receptor and Survival motor neuron protein liga... 1 2
Gastrin/cholecystokinin type B receptor ligand 1-[3-[[2-(3-met... 2 12
Gonadotropin-releasing hormone receptor ligand SureCN5756131 f... 5 7
Histamine H3 receptor ligand 5-[4-[3-[(2R)-2-methylpyrrolidin-... 2 3
Cathepsin K inhibitor (1R,2R)-N-(cyanomethyl)-2-[4-(3-methoxyp... 2 1
5-hydroxytryptamine receptor 1A and Alpha-1B adrenergic recept... 6 11
Urotensin-2 receptor and Cytochrome P450 3A4 ligand 5-chloro-3... 2 1
Delta-type opioid receptor and Kappa-type opioid receptor liga... 5 0
Sigma non-opioid intracellular receptor 1 and 5-hydroxytryptam... 1 0
Metabotropic glutamate receptor 5 ligand AGN-PC-0760YQ family 3 0
P2X purinoceptor 7 inhibitor SureCN3722920 family 4 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00310689 CHEMBL107772 Bioactive (E)-but-2-enedioic acid;[4-chloro-3-(4-methylpiperazin-1-yl)phenyl] 4-(2-methylphenyl)piperazine-1-carboxylate
CFAMM00310678 CHEMBL2218474 Bioactive AGN-PC-088FOA

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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