CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM3537
Family Name D(2) dopamine receptor and 5-hydroxytryptamine receptor 1A ligand AGN-PC-075M8H family
No. of Seeds 1 No. of Other Members 1
Family Centroid CFAMM00180976 Functional Category Bioactive
Superfamily Mu-type opioid receptor and Delta-type opioid receptor Binder Superfamily 6
Class Class 2081

Cousin Family NamesSeedsMembers
Beta adrenergic receptor ligand monosubstituted indole derivat... 14 475
Melatonin receptor type 1A Ligand Melatonin Family 20 988
Calcium-activated potassium channel subunit alpha-1 Ligand Qui... 3 46
cGMP-specific 3',5'-cyclic phosphodiesterase Inhibitor Papaver... 53 741
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor Lig... 11 49
Protein kinase C theta type Inhibitor 4-(1h-indol-5-yloxy)-5-s... 21 194
Reverse transcriptase Inhibitor 3'thiacytidine Family 4 29
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 13 22
Hemoglobin subunit alpha Inhibitor 2-[(2-methoxy-5-methylpheno... 5 48
Hemoglobin subunit alpha Inhibitor 4-[(5-methoxy-2-methylpheno... 3 12
Platelet-derived growth factor receptor alpha and Platelet-der... 2 9
Platelet-derived growth factor receptor beta and Epidermal gro... 3 7
Platelet-derived growth factor receptor alpha and Platelet-der... 2 14
Alpha-1A adrenergic receptor Ligand RS-17053 Family 9 6
D(2) dopamine receptor Ligand SLV-314 Family 19 69
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor Lig... 4 35
RAC-gamma serine/threonine-protein kinase Inhibitor A-443654 F... 67 59
5-hydroxytryptamine receptor 2A and Amine oxidase [flavin-cont... 4 32
5-hydroxytryptamine receptor 2A and Alpha-2A adrenergic recept... 4 29
Metabotropic glutamate receptor 5 Ligand 7-(3,5-dimethoxypheny... 2 7
5-hydroxytryptamine receptor 1A and Sodium-dependent serotonin... 17 69
cAMP-specific 3',5'-cyclic phosphodiesterase 4D and cAMP-speci... 3 1
Proto-oncogene tyrosine-protein kinase Src inhibitor SureCN525... 8 8
5-hydroxytryptamine receptor 1A and Sodium-dependent serotonin... 3 0
Sodium-dependent serotonin transporter inhibitor SureCN6575591... 2 0
Sodium-dependent serotonin transporter inhibitor AGN-PC-075G9A... 3 2
Platelet-derived growth factor receptor beta and Macrophage co... 1 4
Renin inhibitor SureCN6043852 family 2 0
Substance-P receptor ligand AGN-PC-00FIT5 family 3 11
Lanosterol synthase inhibitor AGN-PC-07BZTX family 2 0
Small conductance calcium-activated potassium channel protein ... 2 2
Cytochrome P450 2D6 inhibitor AGN-PC-0509UI family 1 2


CFAM Mol ID

External ID

Functional Category

Molecule Name


Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27513 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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