CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM3542
Family Name D(2) dopamine receptor and D(1A) dopamine receptor ligand (2R,3R)-2-amino-3-phenyl-2,3-dihydro-1H-inden-5-ol family
No. of Seeds 3 No. of Other Members 2
Family Centroid CFAMM00348147 Functional Category Bioactive
Superfamily Kappa-type opioid receptor Ligand Dezocine Superfamily
Class Class 62

Cousin Family NamesSeedsMembers
D(2) dopamine receptor ligand catecholamine Dopamine family 9 170
Beta adrenergic receptor ligand catecholamine group Isoprotere... 7 130
Opioid receptor ligand opiate Levorphanol Family 18 537
Alpha adrenergic receptor ligand catecholamine Phenylephrine F... 4 39
Beta-2 adrenergic receptor ligand catecholamine Orciprenaline ... 13 13
D(1A) dopamine receptor Ligand Fenoldopam Family 4 78
D(1B) dopamine receptor Ligand Apomorphine Family 30 271
Muscarinic acetylcholine receptor M3 Ligand Tolterodine Family 8 171
Kappa-type opioid receptor Ligand Dezocine Family 36 46
Noradrenergic re-uptake Inhibitor Desvenalfaxine Succinate Family 2 4
Eptazocine Hbr family 6 8
Noradrenergic re-uptake and Opioid receptor Ligand Tapentadol ... 21 79
CORT-108297 family 46 44
5-hydroxytryptamine receptor 1A Ligand (s)-uh-301 Family 35 20
D(2) dopamine receptor and D(1A) dopamine receptor Ligand A-70... 16 27
Amine oxidase [flavin-containing] B Inhibitor 5-hydroxy-n-prop... 3 5
5-hydroxytryptamine receptor 2A Ligand 3-methoxy-9-aminomethyl... 7 14
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 44 3
Alpha-2A adrenergic receptor and Alpha-2B adrenergic receptor ... 3 4
Alpha-2A adrenergic receptor and Alpha-2B adrenergic receptor ... 1 2
Matrix metalloproteinase-9 and 72 kDa type IV collagenase inhi... 2 4
Sodium-dependent dopamine transporter and Sodium-dependent ser... 1 0
Alpha-2B adrenergic receptor and Alpha-2C adrenergic receptor ... 1 0
Glutamate receptor ionotropic, NMDA 1 and Glutamate receptor i... 2 2


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00348151 CHEMBL334191 Bioactive AGN-PC-074BRM
CFAMM00348150 CHEMBL336366 Bioactive (1R,2R)-2-amino-1-phenyl-2,3-dihydro-1H-inden-5-ol
CFAMM00348147 CHEMBL135224 Bioactive (2R,3R)-2-amino-3-phenyl-2,3-dihydro-1H-inden-5-ol

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27257 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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