CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM3549
Family Name Reverse transcriptase/RNaseH inhibitor AC1MHDM5 family
No. of Seeds 2 No. of Other Members 0
Family Centroid CFAMM00348192 Functional Category Bioactive
Superfamily Reverse transcriptase/RNaseH and Huntingtin Binder Superfamily
Class Class 873

Cousin Family NamesSeedsMembers
cGMP-specific 3',5'-cyclic phosphodiesterase Inhibitor Papaver... 53 741
Histamine H1 receptor Ligand Mepyramine Family 5 65
Smoothened homolog Inhibitor LDE225 Family 3 76
Tissue-type plasminogen activator Inhibitor N-(7-benzyloxy-iso... 4 37
Cytochrome P450 11B1, mitochondrial and Aromatase Inhibitor 3-... 12 3
Steroid 17-alpha-hydroxylase/17,20 lyase and Cytochrome P450 1... 7 6
Reverse transcriptase Inhibitor PT-115 Family 7 19
Urokinase-type plasminogen activator and Plasminogen inhibitor... 1 2
D(3) dopamine receptor and D(2) dopamine receptor ligand AGN-P... 3 4
Reverse transcriptase/RNaseH inhibitor 1-[2-(6-chloro-3-ethoxy... 7 5
cAMP-specific 3',5'-cyclic phosphodiesterase 4A inhibitor Sure... 14 8
TRAF2 and NCK-interacting protein kinase inhibitor 4-methoxy-3... 4 1
Reverse transcriptase/RNaseH inhibitor 1-(5-chloropyridin-2-yl... 3 0
Reverse transcriptase/RNaseH inhibitor PETT deriv. 14 family 1 0
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase inhibitor 1-... 1 3
Urokinase-type plasminogen activator and Plasminogen inhibitor... 1 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00348192 CHEMBL135254 Bioactive AC1MHDM5
CFAMM00348191 CHEMBL435600 Bioactive 181305-34-0

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27518 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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