CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM3551
Family Name Neuropeptide S receptor and Prelamin-A/C ligand CHEMBL1352632 family
No. of Seeds 1 No. of Other Members 25
Family Centroid CFAMM00348215 Functional Category Bioactive with Natural Product
Superfamily Prelamin-A/C and Cholinesterase Binder Superfamily
Class Class 3833

Cousin Family NamesSeedsMembers
D(4) dopamine receptor Ligand PD-165167 Family 2 96
Beta-2 adrenergic receptor Ligand Olodaterol Family 16 27
Peptidyl-prolyl cis-trans isomerase A Inhibitor 7-amino-4-meth... 4 59
Mineralocorticoid receptor and Androgen receptor Ligand AL-43 ... 79 235
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor Lig... 25 50
Oxytocin receptor and Vasopressin V1a receptor Ligand L-371257... 8 92
Cytochrome P450 1B1 Inhibitor N-(2,4-dimethoxy-phenyl)-3,5-dim... 1 110
Alpha-1A adrenergic receptor Ligand Naftopidil Family 15 119
Amine oxidase [flavin-containing] B Inhibitor N-methyl-n-pheny... 6 25
Renin Inhibitor Ro-66-1168 Family 10 30
Galanin receptor type 1 and Galanin receptor type 2 Ligand Gal... 55 132
Cytochrome P450 2D6 Inhibitor 4-methylaminomethyl-7-methoxycou... 3 80
Aromatase Inhibitor 2,3,4-trimethoxy-4'-amino-trans-stilbene F... 9 14
Aromatase Inhibitor 3,5-diacetoxy-4'-amino-trans-stilbene Family 1 1
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 21 13
Reverse transcriptase Inhibitor 10-propyl-10h-dibenzo[b,f][1,4... 9 60
Acetylcholinesterase Inhibitor 6-methyl-4-(4-phenylpiperazin-1... 6 622
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor lig... 14 12
D(4) dopamine receptor and D(2) dopamine receptor ligand 7-[[4... 1 23
Androgen receptor ligand (6R,7R)-6,7-diethyl-4-(trifluoromethy... 15 20
Amine oxidase [flavin-containing] B and Amine oxidase [flavin-... 4 65
D(4) dopamine receptor and D(3) dopamine receptor ligand 3-ben... 5 334
Thyroid hormone receptor beta and Thyroid hormone receptor alp... 11 26
Delta-type opioid receptor and Mu-type opioid receptor ligand ... 2 0
Acetylcholinesterase and Cholinesterase inhibitor [3-[4-(3,4-d... 3 18
C-C chemokine receptor type 1 ligand N-[2-[(2S)-3-(5-chlorospi... 5 0
C-C chemokine receptor type 1 ligand N-[2-[(2S)-3-(5-chlorospi... 4 0
C-C chemokine receptor type 1 ligand N-[2-[(2S)-2-amino-3-(5-f... 3 0
Nociceptin receptor and Mu-type opioid receptor ligand SureCN7... 13 22
Alpha-1A adrenergic receptor and Alpha-1B adrenergic receptor ... 1 5
D(4) dopamine receptor and D(3) dopamine receptor ligand 3-[(4... 3 53
D(4) dopamine receptor and D(3) dopamine receptor ligand 3-ben... 3 2
Acetylcholinesterase and Butyrylcholinesterase inhibitor [3-[[... 1 65
Beta-2 adrenergic receptor and Beta-1 adrenergic receptor liga... 8 0
Beta-2 adrenergic receptor and Beta-1 adrenergic receptor liga... 9 0
D(4) dopamine receptor ligand 8-methoxy-3-[(4-nitrophenyl)meth... 1 1
3-oxo-5-alpha-steroid 4-dehydrogenase 1 inhibitor AGN-PC-007ZS... 3 3
Alpha-1D adrenergic receptor and Alpha-1A adrenergic receptor ... 2 9
Beta-secretase 1 inhibitor AGN-PC-00QBHE family 1 0
5-hydroxytryptamine receptor 2A and D(2) dopamine receptor lig... 2 6
Pol polyprotein inhibitor AC1L9TLB family 1 0
Trypanothione reductase inhibitor 3-(2-chlorophenothiazin-10-y... 1 0
Progesterone receptor ligand 6-(4-chlorophenyl)-7-(diethylamin... 2 0
Cytochrome P450 2D6 inhibitor 2-[(3-butoxyphenoxy)methyl]-3-me... 1 0
Acetylcholinesterase inhibitor 4-[(2-methoxyanilino)methyl]-[1... 2 4
Endothelin B receptor and Endothelin-1 receptor ligand AGN-PC-... 3 1
D(1A) dopamine receptor and D(3) dopamine receptor ligand 7-[3... 1 12
NP 3-(2-(3,4-dihydroquinolin-1(2h)-yl)-2-oxoethyl)-7,8-dihydro... 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name


Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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