CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM3594
Family Name Prostaglandin D2 receptor ligand 3-[2-methoxy-6-[2-(4-methoxyphenyl)ethylamino]pyrimidin-4-yl]benzenesulfonamide family
No. of Seeds 2 No. of Other Members 12
Family Centroid CFAMM00348865 Functional Category Bioactive
Superfamily Beta-lactamase and Retinal dehydrogenase 1 Binder Superfamily 4
Class Class 3566

Cousin Family NamesSeedsMembers
Epidermal growth factor receptor Ligand Gefitinib Family 26 600
Corticotropin-releasing factor receptor 1 Ligand CRF-1 Antagon... 29 421
Receptor tyrosine-protein kinase erbB-2 Inhibitor CP-724714 Fa... 4 180
SB1518 family 7 103
Tyrosine kinase Inhibitor PKI166 Family 17 198
Peptide deformylase, mitochondrial Inhibitor 5-(4-methoxypheno... 5 61
Angiopoietin-1 receptor and Tyrosine-protein kinase Lck Inhibi... 3 64
Melanin-concentrating hormone receptor 1 Ligand Gnf-pf-2322 Fa... 3 95
Melanin-concentrating hormone receptor 1 Ligand ADS-102891 Family 6 51
Fatty-acid amide hydrolase 1 Inhibitor BMS-1 Family 5 22
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 17 49
Sodium channel protein type 5 subunit alpha Ligand Enecadin Fa... 1 11
cGMP-specific 3',5'-cyclic phosphodiesterase Inhibitor SK&F-96... 5 83
Alpha-1B adrenergic receptor and Alpha-1D adrenergic receptor ... 6 35
Serine/threonine-protein kinase mTOR and Phosphatidylinositol ... 8 1
Bifunctional dihydrofolate reductase-thymidylate synthase inhi... 5 45
Adenosine kinase inhibitor 5-[3-(4-methoxyphenyl)propyl]-6-[2-... 2 11
Survival motor neuron protein inhibitor CHEMBL1307497 family 1 2
Prelamin-A/C and Nuclear receptor ROR-gamma ligand CHEMBL13704... 1 7
D(3) dopamine receptor and D(2) dopamine receptor ligand AGN-P... 3 14
Bifunctional dihydrofolate reductase-thymidylate synthase and ... 6 13
Methionine--tRNA ligase inhibitor 2-[3-[(2-ethoxy-5-iodo-3-met... 9 32
Methionine--tRNA ligase inhibitor 2-[3-[(5-bromo-2-ethoxy-3-me... 9 11
Prostaglandin D2 receptor ligand 2-[3-[2-methoxy-6-[2-(4-metho... 4 12
Prostaglandin D2 receptor ligand 2-methoxy-N-[2-(4-methoxyphen... 2 5
Prostaglandin D2 receptor ligand 1-[3-[2-methoxy-6-[2-(4-metho... 6 16
Prostaglandin D2 receptor ligand 2-methoxy-N-[2-(4-methoxyphen... 3 21
Adenosine receptor A3 ligand AGN-PC-08WSLM family 5 22
Adenosine receptor A1 and Adenosine receptor A3 ligand AGN-PC-... 6 8
Epidermal growth factor receptor and Receptor tyrosine-protein... 6 9
Integrin beta-1 and Integrin alpha-4 inhibitor SureCN2059024 f... 6 3
Insulin-like growth factor 1 receptor ligand 3qqu family 2 12
Vascular endothelial growth factor receptor 2 ligand urea deri... 2 1
Melanin-concentrating hormone receptor 1 ligand (E)-N-[2-[4-(1... 1 1
Mu-type opioid receptor and Nitric oxide synthase, brain ligan... 3 0
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 2 2
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 18 1
TRAF2 and NCK-interacting protein kinase inhibitor 4-methoxy-3... 4 1
Xanthine dehydrogenase/oxidase inhibitor 5-(2-amino-4-oxo-1H-p... 8 30
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 2 2
Tyrosine-protein kinase ITK/TSK and Tyrosine-protein kinase Lc... 2 6
Tyrosine-protein kinase TXK and Tyrosine-protein kinase Lyn in... 1 1
Melanin-concentrating hormone receptor 1 ligand (1S,3S)-1-N-(4... 3 9
Prostaglandin G/H synthase 2 inhibitor 6-ethoxy-2-(4-methylsul... 5 1
Dihydrofolate reductase inhibitor AC1LAPW3 family 3 0
Bifunctional dihydrofolate reductase-thymidylate synthase inhi... 2 6
5-hydroxytryptamine receptor 3A and 5-hydroxytryptamine recept... 3 10
Adenosine receptor A1 and Adenosine receptor A2a ligand 7-meth... 2 0
Dihydrofolate reductase inhibitor 5-[[4-[2-[4-(4-aminophenyl)s... 1 0
Adenosine receptor A2a ligand AGN-PC-077RYH family 16 5
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor AGN-PC-... 3 1
Prostaglandin G/H synthase 2 and Prostaglandin G/H synthase 1 ... 2 0
Histone-arginine methyltransferase CARM1 inhibitor AGN-PC-07CR... 4 0
Glucokinase inhibitor AGN-PC-03ZE4O family 4 5


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00348866 CHEMBL1644258 Bioactive 2-methoxy-N-[2-(4-methoxyphenyl)ethyl]-6-(3-methylsulfonylphenyl)pyrimidin-4-amine
CFAMM00348865 CHEMBL1644238 Bioactive 3-[2-methoxy-6-[2-(4-methoxyphenyl)ethylamino]pyrimidin-4-yl]benzenesulfonamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27433 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543