CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM363
Family Name Bifunctional epoxide hydrolase 2 and Cytochrome P450 3A4 inhibitor SureCN13211230 family
No. of Seeds 4 No. of Other Members 13
Family Centroid CFAMM00310819 Functional Category Bioactive
Superfamily Cannabinoid receptor 1 and Cannabinoid receptor 2 Binder Superfamily 2
Class Class 3135

Cousin Family NamesSeedsMembers
Substance-P receptor Ligand Vestipitant Family 14 137
Zicronapine family 43 62
Bifunctional epoxide hydrolase 2 Inhibitor 1-cyclohexyl-3-phen... 3 12
Dipeptidyl peptidase 4 Inhibitor 2-(2-chlorophenyl)-2-morpholi... 2 34
Dipeptidyl peptidase 4 Inhibitor N4-(4-chlorobenzyl)-2,4-diami... 10 22
Histamine H3 receptor Ligand N-benzyl-4-cyclopentylpiperazine-... 3 19
Dipeptidyl peptidase 4 Inhibitor 1-benzyl-4-(2,4-dichloropheny... 2 10
Sodium-dependent serotonin transporter Inhibitor Irindalone Fa... 16 9
Aminopeptidase N Inhibitor N1-(4-chlorobenzyl)-2-benzyl-n3-hyd... 9 86
Sodium-dependent dopamine transporter Inhibitor (+/-)-threo-3'... 14 11
Cannabinoid receptor 1 and Cannabinoid receptor 2 ligand AGN-P... 7 9
Cannabinoid receptor 1 and Cannabinoid receptor 2 ligand AGN-P... 2 0
P2X purinoceptor 7 inhibitor (4S)-N-[(2,4-dichlorophenyl)methy... 16 11
Pyruvate kinase PKM and Huntingtin inhibitor CHEMBL1455935 family 1 3
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 3 0
Melanocortin receptor 4 and Melanocortin receptor 5 ligand AC1... 7 31
Ceramide glucosyltransferase and Cytochrome P450 3A4 inhibitor... 7 16
C-C chemokine receptor type 5 ligand N-[(1S)-3-[4-[[2-(2,4-dic... 4 9
Vasopressin V1a receptor ligand N-[(2R)-3-(4-chlorophenyl)-1-[... 6 0
Transporter and Sodium-dependent dopamine transporter inhibito... 6 1
Lysosomal Pro-X carboxypeptidase inhibitor (2S,3S)-2-[(2-amino... 3 3
Renin and Potassium voltage-gated channel subfamily H member 2... 1 0
Renin and Potassium voltage-gated channel subfamily H member 2... 3 2
Oxytocin receptor and Vasopressin V2 receptor ligand (2R)-2-(2... 4 2
Melanocortin receptor 4 and Melanocortin receptor 5 ligand (3R... 6 1
Melanocortin receptor 4 ligand N-[(2R)-3-(4-chlorophenyl)-1-[4... 8 4
Sodium-dependent serotonin transporter and Sodium-dependent no... 3 3
C-C chemokine receptor type 1 ligand N-[(2R)-1-[4-(4-chlorophe... 2 4
Muscarinic acetylcholine receptor M3 and Muscarinic acetylchol... 3 1
Nociceptin receptor and Mu-type opioid receptor ligand AGN-PC-... 1 1
Nociceptin receptor and Mu-type opioid receptor ligand AGN-PC-... 4 1
Nociceptin receptor and Mu-type opioid receptor ligand AGN-PC-... 2 1
C-C chemokine receptor type 5 ligand N-[(1S)-3-[4-[(3,4-dichlo... 1 0
Prostaglandin E synthase inhibitor AGN-PC-09QMEJ family 2 0
Histamine H3 receptor ligand (2S)-N-[(3,4-dichlorophenyl)methy... 2 2
Cannabinoid receptor 1 ligand AGN-PC-078YV8 family 1 2
Histamine H3 receptor ligand AGN-PC-077LOO family 1 4


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00310815 CHEMBL1090397 Bioactive AGN-PC-07ZC5Q
CFAMM00310819 CHEMBL1078265 Bioactive SureCN13211230
CFAMM00310824 CHEMBL1080973 Bioactive SureCN13211246
CFAMM00310823 CHEMBL1080975 Bioactive AGN-PC-07ZBTG

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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