CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM3649
Family Name Disintegrin and metalloproteinase domain-containing protein 17 inhibitor (3R,4S)-1-(cyclopropanecarbonyl)-3-N-hydroxy-4-N-[4-(quinolin-4-yloxymethyl)phenyl]piperidine-3,4-dicarboxamide family
No. of Seeds 2 No. of Other Members 5
Family Centroid CFAMM00349539 Functional Category Bioactive
Superfamily Calcium-activated potassium channel subunit alpha-1 Ligand AVE0118 Superfamily
Class Class 656

Cousin Family NamesSeedsMembers
72 kDa type IV collagenase and Matrix metalloproteinase-9 Inhi... 37 265
5-hydroxytryptamine receptor 1B Ligand GR55562 Family 3 45
Oxysterols receptor LXR-alpha and Oxysterols receptor LXR-beta... 22 57
5-hydroxytryptamine receptor 1D and 5-hydroxytryptamine recept... 14 48
Leukotriene B4 receptor 1 and Leukotriene B4 receptor 2 ligand... 8 21
Disintegrin and metalloproteinase domain-containing protein 17... 3 2
Disintegrin and metalloproteinase domain-containing protein 17... 2 1
Metabotropic glutamate receptor 2 and Metabotropic glutamate r... 3 3
Cytochrome P450 11B2, mitochondrial and Cytochrome P450 11B1, ... 9 7
Disintegrin and metalloproteinase domain-containing protein 17... 44 12
Platelet-derived growth factor receptor beta and Macrophage co... 1 4
Disintegrin and metalloproteinase domain-containing protein 17... 13 3
Disintegrin and metalloproteinase domain-containing protein 17... 16 2
Prothrombin and Coagulation factor X inhibitor N-[3-[(3-fluoro... 1 8
Disintegrin and metalloproteinase domain-containing protein 17... 8 0
Disintegrin and metalloproteinase domain-containing protein 17... 1 0
Disintegrin and metalloproteinase domain-containing protein 17... 2 1
Disintegrin and metalloproteinase domain-containing protein 17... 9 0
Disintegrin and metalloproteinase domain-containing protein 17... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00349536 CHEMBL339380 Bioactive (3R,4S)-1-acetyl-3-N-hydroxy-4-N-[4-[[7-(trifluoromethyl)quinolin-4-yl]oxymethyl]phenyl]piperidine-3,4-dicarboxamide
CFAMM00349539 CHEMBL135766 Bioactive (3R,4S)-1-(cyclopropanecarbonyl)-3-N-hydroxy-4-N-[4-(quinolin-4-yloxymethyl)phenyl]piperidine-3,4-dicarboxamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27518 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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