CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM3654
Family Name 3-oxo-5-alpha-steroid 4-dehydrogenase 2 and 3-oxo-5-alpha-steroid 4-dehydrogenase 1 inhibitor (1S,9aR,11aS)-N-benzhydryl-9a,11a-dimethyl-7-oxo-1,2,3,3a,3b,4,5,8,9,9b,10,11-dodecahydrocyclopenta[i]phenanthridine-1-carboxamide family
No. of Seeds 12 No. of Other Members 8
Family Centroid CFAMM00007876 Functional Category Bioactive
Superfamily 3-oxo-5-alpha-steroid 4-dehydrogenase 1 and 3-oxo-5-alpha-steroid 4-dehydrogenase 2 Binder Superfamily 6
Class Class 3863

Cousin Family NamesSeedsMembers
5-alpha reductase inhibitor azasteroid derivative Dutasteride ... 36 124
5-hydroxytryptamine receptor 3A Ligand Palonosetron Family 12 403
Microsomal triglyceride transfer protein large subunit Inhibit... 15 208
5-hydroxytryptamine receptor 2A Ligand N-(1-(1-phenylethyl)pip... 22 207
Cathepsin K and Cathepsin L1 Inhibitor N-benzoyl-phenylalanyl-... 13 77
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 41 24
3-oxo-5-alpha-steroid 4-dehydrogenase 2 and 3-oxo-5-alpha-ster... 4 8
Neuromedin-K receptor ligand SureCN2477089 family 2 4
Oxytocin receptor and Vasopressin V2 receptor ligand (2R)-2-(2... 4 2
3-oxo-5-alpha-steroid 4-dehydrogenase 2 and 3-oxo-5-alpha-ster... 3 1
3-oxo-5-alpha-steroid 4-dehydrogenase 2 and 3-oxo-5-alpha-ster... 7 0
3-oxo-5-alpha-steroid 4-dehydrogenase 2 and 3-oxo-5-alpha-ster... 4 1
3-oxo-5-alpha-steroid 4-dehydrogenase 2 and 3-oxo-5-alpha-ster... 3 0
3-oxo-5-alpha-steroid 4-dehydrogenase 2 and 3-oxo-5-alpha-ster... 4 1
Histamine H3 receptor ligand Conessine analogue, 13e family 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00349582 CHEMBL88032 Bioactive (1S,9aR,11aS)-N-[1-(4-tert-butylphenyl)cyclohexyl]-9a,11a-dimethyl-7-oxo-1,2,3,3a,3b,4,5,8,9,9b,10,11-dodecahydrocyclopenta[i]phenanthridine-1-carboxamide
CFAMM00349575 CHEMBL314309 Bioactive (1S,9aR,11aS)-N-[1-(4-tert-butylphenyl)cyclopentyl]-9a,11a-dimethyl-7-oxo-1,2,3,3a,3b,4,5,8,9,9b,10,11-dodecahydrocyclopenta[i]phenanthridine-1-carboxamide
CFAMM00349580 CHEMBL306554 Bioactive (1S,9aR,11aS)-N-benzhydryl-5,9a,11a-trimethyl-7-oxo-2,3,3a,3b,4,8,9,9b,10,11-decahydro-1H-cyclopenta[i]phenanthridine-1-carboxamide
CFAMM00349573 CHEMBL88485 Bioactive (1S,9aR,11aS)-N-[1-(4-tert-butylphenyl)cycloheptyl]-9a,11a-dimethyl-7-oxo-1,2,3,3a,3b,4,5,8,9,9b,10,11-dodecahydrocyclopenta[i]phenanthridine-1-carboxamide
CFAMM00349579 CHEMBL308258 Bioactive (1S,9aR,11aS)-9a,11a-dimethyl-7-oxo-N-trityl-1,2,3,3a,3b,4,5,8,9,9b,10,11-dodecahydrocyclopenta[i]phenanthridine-1-carboxamide
CFAMM00349577 CHEMBL77290 Bioactive (1S,9aR,11aS)-N-benzhydryl-6,9a,11a-trimethyl-7-oxo-1,2,3,3a,3b,4,5,8,9,9b,10,11-dodecahydrocyclopenta[i]phenanthridine-1-carboxamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27260 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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