CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM3655
Family Name 5-hydroxytryptamine receptor 1A and Sodium-dependent serotonin transporter ligand SureCN6597937 family
No. of Seeds 3 No. of Other Members 1
Family Centroid CFAMM00349584 Functional Category Bioactive
Superfamily 5-hydroxytryptamine receptor 1A and Sodium-dependent serotonin transporter Binder Superfamily 4
Class Class 1162

Cousin Family NamesSeedsMembers
5-hydroxytryptamine receptor 1A Ligand (s)-way 100135 Family 94 975
Alpha-2C adrenergic receptor Ligand ARC239 Family 15 23
CGMP-inhibited 3',5'-cyclic phosphodiesterase Inhibitor Cilost... 6 202
Vasopressin V1a receptor and Vasopressin V2 receptor Ligand JT... 14 4
5-hydroxytryptamine receptor 1A Ligand NAN-190 Family 14 28
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 20 33
Alpha-1A adrenergic receptor and Alpha-1B adrenergic receptor ... 7 23
5-hydroxytryptamine receptor 1A and Alpha-1A adrenergic recept... 18 12
Alpha-1A adrenergic receptor Ligand RWJ-68141 Family 5 4
Alpha-1A adrenergic receptor Ligand Upidosin Family 8 46
Galanin receptor type 1 and Galanin receptor type 2 Ligand Gal... 55 132
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 21 13
Reverse transcriptase Inhibitor 10-propyl-10h-dibenzo[b,f][1,4... 9 60
5-hydroxytryptamine receptor 1A and Sodium-dependent serotonin... 6 4
Alpha-1A adrenergic receptor and Alpha-1D adrenergic receptor ... 9 22
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor lig... 2 0
5-hydroxytryptamine receptor 1A and Alpha-1B adrenergic recept... 7 12
Alpha-1D adrenergic receptor and Alpha-1A adrenergic receptor ... 12 10
D(3) dopamine receptor and D(1A) dopamine receptor ligand N-[(... 6 14
5-hydroxytryptamine receptor 1A and Sodium-dependent serotonin... 1 2
5-hydroxytryptamine receptor 1A and Alpha-1B adrenergic recept... 4 8
Alpha-1B adrenergic receptor and Alpha-1D adrenergic receptor ... 7 4
Estrogen receptor and Estrogen receptor beta ligand AGN-PC-075... 16 3
D(3) dopamine receptor and D(2) dopamine receptor ligand AGN-P... 4 1
Alpha-1D adrenergic receptor and Alpha-1A adrenergic receptor ... 8 1
D(3) dopamine receptor and D(4) dopamine receptor ligand N-[4-... 6 16
Alpha-1D adrenergic receptor and Alpha-1A adrenergic receptor ... 5 0
Alpha-1D adrenergic receptor and Alpha-1A adrenergic receptor ... 2 0
D(3) dopamine receptor and D(2) dopamine receptor ligand N-[4-... 5 8
D(3) dopamine receptor and D(2) dopamine receptor ligand N-[4-... 2 0
D(2) dopamine receptor and 5-hydroxytryptamine receptor 1A lig... 2 10
D(4) dopamine receptor ligand 2-[4-(thiophen-2-ylmethyl)pipera... 1 1
D(3) dopamine receptor and D(2) dopamine receptor ligand AGN-P... 2 1
Survival motor neuron protein inhibitor N-(2-methoxyphenyl)-2-... 1 1
Estradiol 17-beta-dehydrogenase 2 inhibitor 5-(2-fluoro-3-meth... 1 3


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00349584 CHEMBL135802 Bioactive SureCN6597937
CFAMM00349583 CHEMBL336592 Bioactive 3-[4-(2-methoxyphenyl)piperazin-1-yl]-1-thiophen-2-ylpropan-1-one

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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