CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM3663
Family Name Beta-3 adrenergic receptor and Beta-2 adrenergic receptor ligand AGN-PC-073TKA family
No. of Seeds 4 No. of Other Members 1
Family Centroid CFAMM00349620 Functional Category Bioactive
Superfamily Beta-lactamase and Prelamin-A/C Binder Superfamily 9
Class Class 122

Cousin Family NamesSeedsMembers
Dihydropterin pyrophosphokinase-dihydropteroate synthase inhib... 5 60
Mast/stem cell growth factor receptor Kit and Vascular endothe... 6 34
Neuropeptide Y receptor type 5 Ligand CGP71683A Family 5 74
Peptide deformylase, mitochondrial Inhibitor 5-phenylsulfanyl-... 5 23
5-hydroxytryptamine receptor 6 Ligand 4-(1h-indol-1-ylsulfonyl... 7 79
Plasminogen and Urokinase-type plasminogen activator Inhibitor... 3 26
Corticosteroid 11-beta-dehydrogenase isozyme 1 Inhibitor 2-(4-... 8 25
Potassium voltage-gated channel subfamily H member 2 Ligand AZ... 21 42
Prostaglandin G/H synthase 2 Inhibitor GW-637185X Family 27 48
Farnesyltransferase beta subunit, putative and Protein farnesy... 12 4
Corticotropin-releasing factor receptor 1 Ligand N-mesityl-6-m... 3 2
Corticosteroid 11-beta-dehydrogenase isozyme 1 Inhibitor PF-91... 8 14
Tyrosine-protein kinase JAK2 inhibitor AGN-PC-07ZB89 family 6 13
Inhibitor of nuclear factor kappa-B kinase subunit beta inhibi... 1 7
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 4 27
Histamine H4 receptor ligand 2-[[6-iodo-2-(4-methylpiperazin-1... 4 2
Carbonic anhydrase 9 and Carbonic anhydrase 2 inhibitor 4-[2-(... 2 6
Neuropeptide Y receptor type 5 ligand SureCN8898853 family 2 3
Sodium-dependent serotonin transporter and 5-hydroxytryptamine... 5 0
Aurora kinase B and Vascular endothelial growth factor recepto... 1 2
Serine/threonine-protein kinase SMG1 and Cyclin-dependent kina... 3 1
Bombesin receptor subtype-3 and Nuclear receptor subfamily 1 g... 12 11
Dihydrofolate reductase inhibitor WR 158122 family 1 0
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 1 3
Focal adhesion kinase 1 and Protein-tyrosine kinase 2-beta inh... 1 1
Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor 4-(4-... 1 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00349620 CHEMBL299719 Bioactive AGN-PC-073TKA
CFAMM00349627 CHEMBL291467 Bioactive AGN-PC-073TK9
CFAMM00349621 CHEMBL433252 Bioactive AGN-PC-073TK8

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

48680 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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