CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM3675
Family Name Receptor-type tyrosine-protein kinase FLT3 ligand 2-(6,7-dimethoxyquinazolin-4-yl)sulfanyl-1,3,4-thiadiazole family
No. of Seeds 3 No. of Other Members 2
Family Centroid CFAMM00349719 Functional Category Bioactive
Superfamily Aurora kinase A and Receptor-type tyrosine-protein kinase FLT3 Binder Superfamily
Class Class 1144

Cousin Family NamesSeedsMembers
Alpha-1D adrenergic receptor Ligand Terazosin Family 28 638
Peptide deformylase, mitochondrial Inhibitor Trimetrexate Family 4 311
Epidermal growth factor receptor Ligand Gefitinib Family 26 600
Vascular endothelial growth factor receptor 2 Ligand Cediranib... 8 38
Abelson tyrosine-protein kinase 2 and Proto-oncogene tyrosine-... 25 40
Angiopoietin-1 receptor and Tyrosine-protein kinase Lck Inhibi... 3 64
Platelet-derived growth factor receptor alpha and Platelet-der... 2 9
Epidermal growth factor receptor Ligand 4-(5-bromoindole-3-yl)... 6 15
Proto-oncogene tyrosine-protein kinase Src inhibitor N-(2,4-di... 3 0
Dual specificity mitogen-activated protein kinase kinase 1 inh... 10 54
Platelet-derived growth factor receptor beta and Platelet-deri... 2 19
Tyrosine-protein kinase Lck inhibitor AGN-PC-073GX8 family 12 1
Amine oxidase [flavin-containing] B and Amine oxidase [flavin-... 1 20
Aurora kinase A inhibitor AGN-PC-00BCUF family 16 43
Nuclear receptor ROR-gamma and 15-hydroxyprostaglandin dehydro... 1 3
Alpha-1D adrenergic receptor and Alpha-1B adrenergic receptor ... 6 9
Survival motor neuron protein and Microtubule-associated prote... 1 20
Adenosine receptor A1 and Adenosine receptor A3 ligand AGN-PC-... 6 8
Proto-oncogene tyrosine-protein kinase Src inhibitor AC1NS5MA ... 3 4
Vascular endothelial growth factor receptor 2 ligand AGN-PC-00... 4 0
Vascular endothelial growth factor receptor 2 ligand AGN-PC-00... 8 1
Epidermal growth factor receptor ligand SureCN4454332 family 18 5
Transient receptor potential cation channel subfamily V member... 2 4
Dual specificity tyrosine-phosphorylation-regulated kinase 1A ... 4 2
Deoxycytidine kinase inhibitor 2-[5-[4-[(4,6-diaminopyrimidin-... 14 11
Histone-lysine N-methyltransferase EHMT2 inhibitor N-(1-cyclop... 1 2
Vascular endothelial growth factor receptor 2 and Platelet-der... 1 0
Vascular endothelial growth factor receptor 2 ligand 2-aminobe... 1 0
Epidermal growth factor receptor and Receptor tyrosine-protein... 3 7
Vascular endothelial growth factor receptor 2 ligand aminothia... 1 1
DNA-(apurinic or apyrimidinic site) lyase and DNA polymerase b... 1 0
Glucokinase inhibitor AGN-PC-03ZE4O family 4 5
Platelet-derived growth factor receptor beta ligand N-(4-chlor... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00349719 CHEMBL2046726 Bioactive 2-(6,7-dimethoxyquinazolin-4-yl)sulfanyl-1,3,4-thiadiazole
CFAMM00349718 CHEMBL2046699 Bioactive 2-(6,7-dimethoxyquinazolin-4-yl)sulfanyl-1,3-thiazole
CFAMM00349717 CHEMBL135902 Bioactive AGN-PC-075M3M

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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