CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM3679
Family Name Prelamin-A/C and Niemann-Pick C1 protein inhibitor CHEMBL1359235 family
No. of Seeds 1 No. of Other Members 16
Family Centroid CFAMM00349738 Functional Category Bioactive
Superfamily NAD-dependent protein deacetylase sirtuin-2 and Huntingtin Binder Superfamily
Class Class 3131

Cousin Family NamesSeedsMembers
Mast/stem cell growth factor receptor Kit and Abelson tyrosine... 6 537
Prothrombin Inhibitor Dabigatran Family 7 182
BIBT986 family 7 96
JAK Inhibitor Momelotinib Family 33 83
Platelet activating factor, putative Inhibitor ABT-491 Family 22 62
Poly [ADP-ribose] polymerase 1 Inhibitor N-(4-phenylthiazol-2-... 6 150
Estrogen receptor beta and Peroxisome proliferator-activated r... 1 1
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 1 2
5-hydroxytryptamine receptor 1F and 5-hydroxytryptamine recept... 8 12
Insulin receptor and Tyrosine-protein kinase Lck ligand AGN-PC... 1 1
Adenosine receptor A2a ligand AGN-PC-01LVXW family 2 25
Adenosine receptor A2a ligand SureCN14156209 family 3 2
Cell division cycle 7-related protein kinase inhibitor pyrrolo... 4 10
Peroxisome proliferator-activated receptor gamma ligand 1-[(4-... 7 29
Histamine H3 receptor and Potassium voltage-gated channel subf... 7 1
Histamine H3 receptor ligand SureCN2878688 family 8 1
Dipeptidyl peptidase 4 and Cytochrome P450 3A4 inhibitor 6-[(3... 10 0
Protein kinase C zeta type and Inhibitor of nuclear factor kap... 1 6
Melanin-concentrating hormone receptor 1 and Muscarinic acetyl... 8 2
Melanocortin receptor 4 ligand AGN-PC-076AMO family 17 8
Melanocortin receptor 4 ligand AGN-PC-076ANF family 1 0
Disintegrin and metalloproteinase domain-containing protein 17... 3 0
Disintegrin and metalloproteinase domain-containing protein 17... 10 4
Alpha-1A adrenergic receptor and Alpha-1B adrenergic receptor ... 3 0
Coagulation factor X inhibitor SureCN8290907 family 2 2
Cyclin-dependent kinase 2 and Potassium voltage-gated channel ... 12 7
Tyrosine-protein kinase ITK/TSK inhibitor AGN-PC-077RDJ family 15 1
Tyrosine-protein kinase ITK/TSK inhibitor AGN-PC-00A4QJ family 12 6
Tyrosine-protein kinase ITK/TSK and Insulin receptor ligand N-... 2 17
Tyrosine-protein kinase ITK/TSK and Insulin receptor ligand AG... 7 11
Tyrosine-protein kinase ITK/TSK and Insulin receptor ligand AG... 5 1
Melanin-concentrating hormone receptor 1 ligand SureCN3832854 ... 3 2
Platelet-derived growth factor receptor beta and Fibroblast gr... 10 0
Melanin-concentrating hormone receptor 1 ligand SureCN3834858 ... 2 1
Tyrosine-protein kinase ITK/TSK inhibitor AGN-PC-04XL74 family 1 0
Platelet-derived growth factor receptor beta and Fibroblast gr... 2 1
Tyrosine-protein kinase ITK/TSK inhibitor SureCN6632543 family 1 2


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00349732 CHEMBL457706 Bioactive AGN-PC-04XL6R

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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