CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM36960
Family Name Cytochrome P450 2C19 inhibitor CHEMBL1449918 family
No. of Seeds 1 No. of Other Members 0
Family Centroid CFAMM00508684 Functional Category Bioactive
Superfamily Cytochrome P450 2C19 and Melanin-concentrating hormone receptor 2 Binder Superfamily
Class Class 3209

Cousin Family NamesSeedsMembers
D(2) dopamine receptor and D(1A) dopamine receptor ligand ergo... 12 720
5-hydroxytryptamine receptor 1B and 5-hydroxytryptamine recept... 4 171
Acetylcholinesterase Inhibitor Tacrine Family 12 515
Histamine H1 receptor Ligand Pheniramine Family 10 380
Potassium voltage-gated channel subfamily KQT member 1 Ligand ... 13 242
D(1B) dopamine receptor Ligand LE-300 Family 65 452
Histone deacetylase 1 Inhibitor Panobinostat Family 5 93
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 6 17
Cannabinoid receptor 2 Ligand JWH-167 Family 25 168
Potassium voltage-gated channel subfamily H member 2 Ligand 5-... 5 14
5-hydroxytryptamine receptor 2A Ligand 8-chloro-1,2,3,4-tetrah... 5 4
Fatty acid-binding protein, adipocyte and Fatty acid-binding p... 3 11
Inosine-5'-monophosphate dehydrogenase 2 Inhibitor 1-methyl-1h... 6 24
Trypsin Inhibitor 1-benzyl-1h-indole-5-carboxamidine Family 4 3
Cholinesterase Inhibitor 9-[9-(beta-carboline-9-yl)nonyl]-beta... 7 7
Kinesin-like protein KIF11 Inhibitor 2-(trifluoromethyl)-9h-ca... 5 0
Sodium-dependent serotonin transporter Inhibitor 3-(3-aminocyc... 94 23
Ribosyldihydronicotinamide dehydrogenase [quinone] Inhibitor N... 6 10
Gamma-aminobutyric acid receptor subunit alpha-1 Ligand 7,12-d... 1 0
Protein kinase C alpha type Inhibitor Dequalinium Analogue Family 1 10
Acetylcholinesterase and Cholinesterase Inhibitor Huprine-tacr... 62 27
Histamine H3 receptor and Potassium voltage-gated channel subf... 3 3
Progesterone receptor and Androgen receptor ligand 5-[4-[(Z)-C... 2 5
D(2) dopamine receptor and 5-hydroxytryptamine receptor 2C lig... 2 3
D(2) dopamine receptor and 5-hydroxytryptamine receptor 1A lig... 5 8
Prostaglandin G/H synthase 2 and Prostaglandin G/H synthase 1 ... 1 1
Nuclear receptor ROR-gamma and Prelamin-A/C ligand CHEMBL14461... 1 18
Indoles Metabolite Ethyl 3-methyl-9H-carbazole-9-carboxylate F... 1 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00508683 CHEMBL2335178 Bioactive 5-[[4-(7,8,9,10-tetrahydro-6H-cyclohepta[b]indol-5-ylmethyl)phenyl]methyl]-7,8,9,10-tetrahydro-6H-cyclohepta[b]indole

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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